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72416 Lrpprc

72416

Lrpprc

leucine-rich PPR-motif containing

protein-coding

Mus musculus

基因描述

Type Description
Definition leucine-rich PPR-motif containing

研究结论

Date Results Publications
2020-11-28 13:12:00 LRPPRC sustains Yap-P27-mediated cell ploidy and P62-HDAC6-mediated autophagy maturation and suppresses genome instability and hepatocellular carcinomas. 32203162
2018-09-08 11:47:00 Study demonstrated that the LRPPRC-SLIRP complex is a global RNA chaperone that stabilizes RNA structures to expose the required sites for translation, stabilization, and polyadenylation. 29146908
2017-07-08 10:09:00 Data suggest NT-Pgc-1alpha (alternative splicing isoform of nuclear protein Pgc-1alpha) is located in mitochondrial matrix in brown adipocytes, specifically enriched at D-loop region of mitochondrial DNA at promoter region of Lrpprc (leucine-rich PPR-motif containing protein); expression of NT-Pgc-1alpha (rather than Pgc-1alpha) in brown adipocytes appears to induce expression of electron transport chain complex proteins. 28473468
2016-05-14 12:19:00 both LRPPRC and SLIRP are required for maintaining mt-mRNA steady-state levels independent of their roles in stabilizing the other partner of the LRPPRC-SLIRP complex. 26247782
2016-02-06 10:14:00 Ectopic expression of LRPPRC in the mouse liver completely interdicted non-alcoholic fatty liver disease, including inflammation. 25933096

名称对应

Type IDs
Synonymous 3110001K13Rik, C76645, Gp130, Lrp130, Lsfc
Gene
UniProtKB-ID: LPPRC_MOUSE
UniprotKB: Q6PB66
UniParc: UPI0000F54B2E
EMBL: AK013955, BC059862, AB027124
Ensembl: ENSMUSG00000024120
KO: mmu:72416
Nucleutide sequences
EMBL-CDS: AAH59862.1, BAB93528.1, BAB29082.2
Ensembl_TRS: ENSMUST00000112308
Protein sequencees
Ensembl_PRO: ENSMUSP00000107927
RefSeq: NP_082509.2, XP_011244945.1
Others
UniRef100: UniRef100_Q6PB66
UniRef90: UniRef90_Q6PB66
UniRef50: UniRef50_P42704
UniGene: Mm.217027
CCDS: CCDS29003.2

全选

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