| Type | Description |
|---|---|
| Definition | INS-IGF2 readthrough |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:50:00 | GWAS of five gynecologic diseases and cross-trait analysis in Japanese. | 31488892 |
| 2019-04-27 12:17:00 | High INS-IGF2 expression is associated with Lung Cancer. | 30803359 |
| 2015-11-21 10:39:00 | We identified three known loci (TCF7L2, HMGA2 and KCNQ1) and two novel loci (HLA-B and INS-IGF2) at genome-wide significance (4.15 x 10(-94) | 25102180 |
| 2015-04-25 10:04:00 | Periconception maternal smoking and low education are associated with dna methylation on INSIGF in the very young child. | 25102259 |
| 2013-12-07 10:56:00 | INS-IGF2 and insulin may share autoantibody-binding sites, thus complicating the notion that insulin is the primary autoantigen in type 1 diabetes. | 23935095 |
| Type | IDs |
|---|---|
| Synonymous | INSIGF |
| Gene |
UniProtKB-ID:
INSR2_HUMAN
UniprotKB:
F8WCM5
UniParc:
UPI00001F9AED
EMBL:
DQ104204,
DQ104205,
AC132217
Ensembl:
ENSG00000129965
KO:
hsa:723961
|
| Nucleutide sequences |
EMBL-CDS:
ABD93452.1,
ABD93453.1
Ensembl_TRS:
ENST00000356578,
ENST00000397270
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000348986,
ENSP00000380440
RefSeq:
NP_001035835.1
|
| Others |
UniRef100:
UniRef100_F8WCM5
UniRef90:
UniRef90_F8WCM5
UniRef50:
UniRef50_F8WCM5
UniGene:
Hs.272259,
Hs.700350,
Hs.716962
CCDS:
CCDS41598.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 31488892 |
GWAS of five gynecologic diseases and cross-trait analysis in Japanese. Eur J Hum Genet Tatsuo Masuda , Siew-Kee Low , Masato Akiyama , Makoto Hirata , Yutaka Ueda , Koichi Matsuda , Tadashi Kimura , Yoshinori Murakami , Michiaki Kubo , Yoichiro Kamatani , Yukinori Okada |
2020-01-01 | - |
| 30803359 |
lncINS-IGF2 Promotes Cell Proliferation and Migration by Promoting G1/S Transition in Lung Cancer. Technol. Cancer Res. Treat. Shenglan Gao , Ziying Lin , Chunyan Li , Yahong Wang , Lawei Yang , Bao'an Zou , Jie Chen , Jianwen Li , Dehui Feng , Zeqing Song , Gang Liu |
2019-01-01 | - |
| 25102180 |
PLoS Genet Maggie C Y Ng , Daniel Shriner , Brian H Chen , Jiang Li , Wei-Min Chen , Xiuqing Guo , Jiankang Liu , Suzette J Bielinski , Lisa R Yanek , Michael A Nalls , Mary E Comeau , Laura J Rasmussen-Torvik , Richard A Jensen , Daniel S Evans , Yan V Sun , Ping An , Sanjay R Patel , Yingchang Lu , Jirong Long , Loren L Armstrong , Lynne Wagenknecht , Lingyao Yang , Beverly M Snively , Nicholette D Palmer , Poorva Mudgal , Carl D Langefeld , Keith L Keene , Barry I Freedman , Josyf C Mychaleckyj , Uma Nayak , Leslie J Raffel , Mark O Goodarzi , Y-D Ida Chen , Herman A Taylor , Adolfo Correa , Mario Sims , David Couper , James S Pankow , Eric Boerwinkle , Adebowale Adeyemo , Ayo Doumatey , Guanjie Chen , Rasika A Mathias , Dhananjay Vaidya , Andrew B Singleton , Alan B Zonderman , Robert P Igo , John R Sedor , FIND Consortium , Edmond K Kabagambe , David S Siscovick , Barbara McKnight , Kenneth Rice , Yongmei Liu , Wen-Chi Hsueh , Wei Zhao , Lawrence F Bielak , Aldi Kraja , Michael A Province , Erwin P Bottinger , Omri Gottesman , Qiuyin Cai , Wei Zheng , William J Blot , William L Lowe , Jennifer A Pacheco , Dana C Crawford , eMERGE Consortium , DIAGRAM Consortium , Elin Grundberg , MuTHER Consortium , Stephen S Rich , M Geoffrey Hayes , Xiao-Ou Shu , Ruth J F Loos , Ingrid B Borecki , Patricia A Peyser , Steven R Cummings , Bruce M Psaty , Myriam Fornage , Sudha K Iyengar , Michele K Evans , Diane M Becker , W H Linda Kao , James G Wilson , Jerome I Rotter , Michèle M Sale , Simin Liu , Charles N Rotimi , Donald W Bowden , MEta-analysis of type 2 DIabetes in African Americans Consortium |
2014-08-01 | - |
| 23935095 |
Autoimmunity against INS-IGF2 protein expressed in human pancreatic islets. J Biol Chem Norio Kanatsuna , Jalal Taneera , Fariba Vaziri-Sani , Nils Wierup , Helena Elding Larsson , Ahmed Delli , Hanna Skärstrand , Alexander Balhuizen , Hedvig Bennet , Donald F Steiner , Carina Törn , Malin Fex , à ke Lernmark |
2013-10-04 | - |
| 25102259 |
J Dev Orig Health Dis S A Obermann-Borst , B T Heijmans , P H C Eilers , E W Tobi , E A P Steegers , P E Slagboom , R P M Steegers-Theunissen |
2012-10-01 |
INS-IGF2
|
| 21829393 |
Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases. PLoS Genet. Vincent Plagnol , Joanna M M Howson , Deborah J Smyth , Neil Walker , Jason P Hafler , Chris Wallace , Helen Stevens , Laura Jackson , Matthew J Simmonds , Type 1 Diabetes Genetics Consortium , Polly J Bingley , Stephen C Gough , John A Todd |
2011-08-01 | - |
| 20628086 |
Diabetes Care Swneke D Bailey , Changchun Xie , Ron Do , Alexandre Montpetit , Rafael Diaz , Viswanathan Mohan , Bernard Keavney , Salim Yusuf , Hertzel C Gerstein , James C Engert , Sonia Anand , DREAM investigators |
2010-10-01 | - |
| 20967262 |
Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. PLoS ONE Tulika Prakash , Vineet K Sharma , Naoki Adati , Ritsuko Ozawa , Naveen Kumar , Yuichiro Nishida , Takayoshi Fujikake , Tadayuki Takeda , Todd D Taylor |
2010-01-01 |
LIMS3-LOC440895,
GPR75-ASB3,
TMED7-TICAM2,
TSNAX-DISC1,
IQCJ-SCHIP1,
LY75-CD302,
ARPC4-TTLL3,
MSANTD3-TMEFF1,
RBM14-RBM4,
APITD1-CORT,
ATP5J2-PTCD1,
ABHD14A-ACY1,
CCDC169-SOHLH2,
RNF103-CHMP3,
TMEM110-MUSTN1,
EPPIN-WFDC6,
C15orf38-AP3S2,
NT5C1B-RDH14,
INMT-FAM188B,
SLX1A-SULT1A3,
SLX1B-SULT1A4,
PHOSPHO2-KLHL23,
SEPT5-GP1BB,
FPGT-TNNI3K,
BLOC1S5-TXNDC5,
EEF1E1-BLOC1S5,
RPL17-C18orf32,
TGIF2-C20orf24,
GIMAP1-GIMAP5,
GJA9-MYCBP,
MROH7-TTC4,
PMF1-BGLAP,
TMEM56-RWDD3,
BORCS7-ASMT,
TMX2-CTNND1,
SAA2-SAA4,
ARL2-SNX15,
HSPB2-C11orf52,
BLOC1S1-RDH5,
POC1B-GALNT4,
FKBP1A-SDCBP2,
KLRC4-KLRK1,
ARMCX5-GPRASP2,
NEDD8-MDP1,
BCL2L2-PABPN1,
SERF2-C15ORF63,
RPL36A-HNRNPH2,
CORO7-PAM16,
TEN1-CDK3,
RAD51L3-RFFL,
RNASEK-C17orf49,
TMEM256-PLSCR3,
ZNF559-ZNF177,
RPS10-NUDT3,
ZNF816-ZNF321P,
HSPE1-MOB4,
CKLF-CMTM1,
SYNJ2BP-COX16,
CHURC1-FNTB,
MIA-RAB4B,
RAB4B-EGLN2,
ZNF625-ZNF20,
NPHP3-ACAD11,
NDUFC2-KCTD14,
COMMD3-BMI1,
MSH5-SAPCD1,
INO80B-WBP1,
MINOS1-NBL1,
ATP6V1G2-DDX39B,
PIR-FIGF,
PPT2-EGFL8,
C8orf44-SGK3,
ZHX1-C8orf76,
RTEL1-TNFRSF6B,
ZNF670-ZNF695,
UBE2F-SCLY,
FXYD6-FXYD2,
ZNF664-FAM101A,
ARHGAP19-SLIT1,
FAM24B-CUZD1,
PRH1-PRR4,
BIVM-ERCC5,
DYX1C1-CCPG1,
TVP23C-CDRT4,
SENP3-EIF4A1,
P2RX5-TAX1BP3,
SLMO2-ATP5E,
APOC4-APOC2,
MAGEA10-MAGEA5,
TNFAIP8L2-SCNM1,
HOXA10-HOXA9,
URGCP-MRPS24,
STX16-NPEPL1,
HNRNPUL2-BSCL2,
ISY1-RAB43,
TM4SF19-TCTEX1D2,
C1QTNF3-AMACR,
FAM47E-STBD1,
RAET1E-AS1
|
| 19913121 |
Am. J. Hum. Genet. Philippa J Talmud , Fotios Drenos , Sonia Shah , Tina Shah , Jutta Palmen , Claudio Verzilli , Tom R Gaunt , Jacky Pallas , Ruth Lovering , Kawah Li , Juan Pablo Casas , Reecha Sofat , Meena Kumari , Santiago Rodriguez , Toby Johnson , Stephen J Newhouse , Anna Dominiczak , Nilesh J Samani , Mark Caulfield , Peter Sever , Alice Stanton , Denis C Shields , Sandosh Padmanabhan , Olle Melander , Claire Hastie , Christian Delles , Shah Ebrahim , Michael G Marmot , George Davey Smith , Debbie A Lawlor , Patricia B Munroe , Ian N Day , Mika Kivimaki , John Whittaker , Steve E Humphries , Aroon D Hingorani , ASCOT investigators , NORDIL investigators , BRIGHT Consortium |
2009-11-01 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
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| 排名 | 研究人员 | 文献 |
|---|---|---|
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