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723944 Mir200c

723944

Mir200c

microRNA 200c

ncRNA

Mus musculus

基因描述

Type Description
Definition microRNA 200c

研究结论

Date Results Publications
2020-06-06 11:43:00 Our study is the first to show that fascin-1 plays a critical role in renal fibrosis; MiR-200b/c family could inhibit renal fibrosis through modulating EMT process by directly targeting fascin-1/CD44 axis 32220622
2020-02-22 11:53:00 miR-200c inhibition repressed the production of proinflammatory cytokines (TGF-beta, TNF-alpha, and IL-1alpha) via inhibiting NF-kappaB and Smad2 activation in NHKs exposed to IR. 31346357
2019-09-07 10:08:00 The miR-200c/141 cluster regulated breast cancer stem cells heterogeneity and promoted the epithelial-mesenchymal transformation-like breast cancer stem cells generation, which resulted in increased tumor metastasis and inhibited tumor growth by directly upregulating the target gene homeodomain-interacting protein kinase 1 (HIPK1) and sequential beta-catenin activation. 30613263
2019-07-13 10:08:00 We identified miR-200 family members, in particular miR- 200c, as CD-enriched miRNAs and show that downregulation of these miRNAs is associated with partial EMT in the CDs. 29021386
2019-04-27 10:21:00 disrupting the in vivo regulation of Zeb1 by miR-200c is sufficient to drive epithelial-to-mesenchymal transition, thus highlighting the importance of this axis in tumor progression and invasion. 30405106

名称对应

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Type IDs
Synonymous Mirn200c, mir-200c