| Type | Description |
|---|---|
| Definition | APC membrane recruitment 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-10-26 11:17:00 | analysis provides a novel model for WTX-caused bone diseases and explains on the molecular level how truncation mutations in this gene may retain some of WTX-protein functions. | 29329488 |
| 2015-08-29 11:15:00 | WTX stabilized chromatin binding by TRIM28 and contributed to transcriptional repression of repetitive sequences by TRIM28 in mouse embryonic stem cells. | 25882849 |
| 2011-07-16 11:30:00 | The constellation of anomalies in Wtx null mice suggests that this tumor suppressor broadly regulates mesenchymal progenitor cells in multiple tissues. | 21571217 |
| 2010-01-21 00:00:00 | The observed phenotypic discordance dependent upon whether a mutation is germline or occurs somatically suggests the existence of temporal or spatial constraints on the action of WTX during tumorigenesis. | 19079258 |
| Type | IDs |
|---|---|
| Synonymous | 2810002O09Rik, AW492303, Fam123b, Wtx |
| Gene |
UniProtKB-ID:
AMER1_MOUSE
UniprotKB:
Q7TS75
UniParc:
UPI0000EDA2D5
EMBL:
AK012651,
AK049774,
AL671765,
BC053442
Ensembl:
ENSMUSG00000050332
KO:
mmu:72345
|
| Nucleutide sequences |
EMBL-CDS:
BAC25373.1,
BAC33914.1,
AAH53442.1
Ensembl_TRS:
ENSMUST00000084535
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000109502
RefSeq:
NP_780388.2
|
| Others |
UniRef100:
UniRef100_Q7TS75
UniRef90:
UniRef90_Q7TS75
UniRef50:
UniRef50_Q5JTC6
UniGene:
Mm.182867
CCDS:
CCDS41067.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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