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7224 TRPC5

7224

TRPC5

transient receptor potential cation channel subfamily C member 5

protein-coding

Homo sapiens

基因描述

Type Description
Definition transient receptor potential cation channel subfamily C member 5

研究结论

Date Results Publications
2021-03-13 13:15:00 Regulation of TRPC5 currents by intracellular ATP: Single channel studies. 31994734
2021-02-20 13:28:00 Transient Receptor Potential Canonical 5-Scramblase Signaling Complex Mediates Neuronal Phosphatidylserine Externalization and Apoptosis. 32110987
2020-09-26 13:01:00 Differential PI(4,5)P2 sensitivities of TRPC4, C5 homomeric and TRPC1/4, C1/5 heteromeric channels. 30755645
2020-04-25 12:29:00 Controlling S-palmitoylation of the TRPC5 channel as a potential risk factor can modulate TRPC5 channel expression and activity, providing new insights into a therapeutic strategy for neurodegenerative diseases. 31812495
2019-11-02 11:32:00 Study reports a novel mechanism of self-limiting activation of TRPC1/4 and TRPC1/5 channels by G protein-coupled receptor stimulation. Galphaq protein directly interacts with either TRPC4 or TRPC5 of the heterotetrameric channels to permit activation. Simultaneously, Galphaq-coupled PLCbeta activation leads to the breakdown of PI(4,5)P2, which inhibits activity of TRPC1/4 and 1/5 channels. 30108272

名称对应

Type IDs
Synonymous PPP1R159, TRP5
Gene
UniProtKB-ID: TRPC5_HUMAN
UniprotKB: Q9UL62
UniParc: UPI00001374B6
EMBL: AC005191, BC137274, BC137271, CH471120, AF054568, AL049563
Ensembl: ENSG00000072315
KO: hsa:7224
Nucleutide sequences
EMBL-CDS: EAX02630.1, AAC24563.1, AAI37275.1, AAI37272.1, AAF00002.1
Ensembl_TRS: ENST00000262839
Protein sequencees
Ensembl_PRO: ENSP00000262839
RefSeq: NP_036603.1, XP_016885263.1
Others
UniRef100: UniRef100_Q9UL62
UniRef90: UniRef90_Q9UL62
UniRef50: UniRef50_Q9UL62
UniGene: Hs.657709
CCDS: CCDS14561.1

全选

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