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72170 Chchd4

72170

Chchd4

coiled-coil-helix-coiled-coil-helix domain containing 4

protein-coding

Mus musculus

基因描述

Type Description
Definition coiled-coil-helix-coiled-coil-helix domain containing 4

研究结论

Date Results Publications
2018-10-27 10:12:00 To test whether differences in the ratio between CHCHD4 and ALR might explain tissue-specific differences in the CHCHD4 redox state, we determined the molar ratio of both proteins in different mouse tissues. Surprisingly, ALR is superstoichiometric over CHCHD4 in most tissues. 29704824
2018-02-17 11:44:00 These results suggest that CHCHD4 haploinsufficiency afforded persistent neuroprotection related to reduced release of mitochondrial intermembrane space proteins. 28492551
2017-05-27 11:07:00 Mechanistically, exercise-induced nuclear transcription factor FOXO3 binds to the CHCHD4 promoter and represses its expression, preventing the translocation of p53 to the mitochondria and thereby increasing p53 nuclear localization. 27687729

名称对应

Type IDs
Synonymous 2410012P20Rik, 2810014D17Rik, AI838740
Gene
UniProtKB-ID: MIA40_MOUSE
UniprotKB: Q8VEA4
UniParc: UPI0000024FB4
EMBL: AK012745, BC019405
Ensembl: ENSMUSG00000034203
KO: mmu:72170
Nucleutide sequences
EMBL-CDS: BAC25375.1, AAH19405.1
Ensembl_TRS: ENSMUST00000040835
Protein sequencees
Ensembl_PRO: ENSMUSP00000041380
RefSeq: NP_598689.1
Others
UniRef100: UniRef100_Q8VEA4
UniRef90: UniRef90_Q8VEA4
UniRef50: UniRef50_Q8VEA4
UniGene: Mm.41622
CCDS: CCDS20367.1

全选

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研究热度

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