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721 C4B

721

C4B

complement C4B (Chido blood group)

protein-coding

Homo sapiens

基因描述

Type Description
Definition complement C4B (Chido blood group)

研究结论

Date Results Publications
2020-10-24 14:10:00 Complement genes contribute sex-biased vulnerability in diverse disorders. 32499649
2020-06-06 13:59:00 Employing a range of biochemical approaches, the authors showed (i) a direct association of C1q to Chandipura virus, (ii) deposition of complement proteins C3b, C4b, and C1q on Chandipura virus, and (iii) virus aggregation. 31315998
2019-11-23 11:01:00 Capsid-deposited C4b neutralizes infection by human adenovirus independent of C2 and C3 but requires C1q antibody engagement. C4b inhibits capsid disassembly, preventing endosomal escape and cytosolic access. 30926239
2019-07-13 10:21:00 Our findings suggest that circulating plasma C4d is a promising new prognostic biomarker in patients with MPM and, moreover, helps to select patients for surgery following induction chemotherapy. 29184132
2019-07-06 12:43:00 The authors conclude that Streptococcus pneumoniae PspA and PspC help the pneumococcus to evade complement attack by binding C4BP and so inactivating C4b. 30323030

名称对应

Type IDs
Synonymous C4B1, C4B12, C4B2, C4B3, C4B5, C4BD, C4B_2, C4F, CH, CO4, CPAMD3
Gene
UniProtKB-ID: CO4B_HUMAN, CO4A_HUMAN
UniprotKB: P0C0L5, P0C0L4
UniParc: UPI0001574E5D, UPI000016A806, UPI00001AF648
EMBL: AY379936, M59815, AY379927, AY379939, U77886, AY379908, AY379918, AY379935, AY379868, AY379943, U77887, AY379866, AY379872, AY379942, AY379924, BC144546, AY379926, AL844853, AY379864, AY379884, AY379954, AL929593, AY379886, AY379916, AY379930, V00502, AL049547, AB209989, AY379940, AY379920, AL645922, AY379928, AY379882, U24578, AY379963, M14824, AY379957, AY379934, BC063289, AY379959, AF019413, BC146673, AY379892, AY379948, AY343497, AY379962, AY379922, AY379910, AY379904, AY379896, AY379900, AY379870, AY379902, AY379925, AY379956, AY379862, AY379874, AY379949, AY379960, AY379912, AY379945, AY379876, AY379958, AY379965, AY379944, BC146849, AY379941, AY379938, AY379914, AY379955, M59816, AY379931, BX679671, K00830, CR936924, AY379888, AY379964, AY379933, AY379860, AY379953, AY379906, AY379878, BC151204, AY379898, X77491, AY379890, AY379951, BC171786, L26261, AY379950, AY379932, AY379966, BC012372, AY379894, AY379929, AY379880, AY379947, K02403, AY379952, K02404, AY379946, AY379937
Ensembl: ENSG00000227746, ENSG00000228267, ENSG00000206340, ENSG00000236625, ENSG00000244731, ENSG00000233312, ENSG00000228454, ENSG00000224389
KO: hsa:100293534, hsa:721, hsa:720
Nucleutide sequences
EMBL-CDS: AAK49811.1, AAR89151.1, AAR89163.1, AAR89087.1, AAR89111.1, AAR89127.1, AAR89134.1, AAR89148.1, AAR89093.1, AAA99717.1, AAR89132.1, AAR89097.1, AAR89119.1, AAR89130.1, AAQ99144.1, AAR89139.1, AAA59651.1, AAR89107.1, AAR89123.1, AAR89144.1, AAR89091.1, AAR89105.1, AAR89099.1, AAR89095.1, AAR89121.1, AAR89101.1, AAB67980.1, AAR89089.1, AAR89117.1, AAR89125.1, AAR89150.1, AAR89145.1, AAR89103.1, AAR89109.1, AAR89115.1, CAB89302.1, AAR89142.1, AAR89136.1, AAR89113.1, AAR89138.1, AAH12372.2, CAA54627.1, AAR89155.1, AAR89164.1, AAR89157.1, AAA51855.1, AAI46674.1, AAR89152.1, AAR89167.1, AAR89166.1, AAR89170.1, AAR89158.1, AAR89154.1, AAI44547.1, AAR89159.1, AAI46850.1, AAR89161.1, AAH63289.1, AAI51205.1, AAR89169.1, AAR89168.1, AAA20121.2, AAR89162.1, AAA36229.1, AAI71786.1, CAA23760.1, AAK49810.1, AAA52292.1, AAR89160.1, AAR89153.1, BAE06071.1, AAB59537.1, AAR89156.1
Ensembl_TRS: ENST00000435500, ENST00000375177, ENST00000435363, ENST00000449788, ENST00000411583, ENST00000498271, ENST00000428956, ENST00000421274, ENST00000383325
Protein sequencees
Ensembl_PRO: ENSP00000364321, ENSP00000412786, ENSP00000415941, ENSP00000407942, ENSP00000414200, ENSP00000372815, ENSP00000396688, ENSP00000420212, ENSP00000388662
RefSeq: NP_001002029.3
Others
UniRef100: UniRef100_P0C0L4, UniRef100_P0C0L5
UniRef90: UniRef90_P0C0L4
UniRef50: UniRef50_P0C0L4
UniGene: Hs.534847, Hs.720022
CCDS: CCDS47405.1, CCDS59005.1, CCDS47404.1

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研究热度

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