| Type | Description |
|---|---|
| Definition | solute carrier family 39 (zinc transporter), member 4 |
| Date | Results | Publications |
|---|---|---|
| 2016-02-27 10:47:00 | While Zip4 was not found to be essential for proper glucose homeostasis and insulin secretion in vivo in mice, this study found that Zip4 mediates increases in cytoplasmic and granular zinc pools and stimulates glucose dependent insulin secretion in-vitro | 25806541 |
| 2012-09-29 11:07:00 | These studies strongly suggest that wasting and lethality in acrodermatitis enteropathica patients reflects the loss-of-function of the intestine zinc transporter ZIP4, which leads to abnormal Paneth cell gene expression | 22737083 |
| 2011-03-12 10:21:00 | Cell migration assays revealed that knockdown of Zip4 in Hepa cells depressed in vitro migration whereas forced over-expression in Hepa cells and MCF-7 cells enhanced in vitro migration | 20957146 |
| 2010-06-14 11:18:00 | ZIP4 physically interacts with tPA, correlating with an increased intracellular zinc influx and lysosomal sequestration after excitotoxin stimulation. Changes in prosurvival signals support the idea that this sequestration results in neuroprotection. | 20463217 |
| 2010-01-21 00:00:00 | Zinc deficiency increased mZIP4 protein levels at the plasma membrane, and this was associated with increased zinc uptake. | 14612438 |
| Type | IDs |
|---|---|
| Synonymous | 1600025H15Rik, AU041686, AWMS2, ZIP4 |
| Gene |
UniProtKB-ID:
S39A4_MOUSE
UniprotKB:
Q78IQ7
UniParc:
UPI00005C8A30,
UPI0000020DD3
EMBL:
BC023498,
AK147107,
AB052762,
AK146977
Ensembl:
ENSMUSG00000063354
KO:
mmu:72027
|
| Nucleutide sequences |
EMBL-CDS:
BAC53795.1,
BAE27581.1,
BAE27679.1,
AAH23498.1
Ensembl_TRS:
ENSMUST00000230977
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000155442
RefSeq:
NP_082340.1,
XP_006521490.1
|
| Others |
UniRef100:
UniRef100_Q78IQ7
UniRef90:
UniRef90_Q78IQ7
UniRef50:
UniRef50_Q6P5W5
UniGene:
Mm.276829
CCDS:
CCDS27578.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员