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72018 Fundc1

72018

Fundc1

FUN14 domain containing 1

protein-coding

Mus musculus

基因描述

Type Description
Definition FUN14 domain containing 1

研究结论

Date Results Publications
2020-09-19 16:30:00 Silencing FUNDC1 alleviates chronic obstructive pulmonary disease by inhibiting mitochondrial autophagy and bronchial epithelium cell apoptosis under hypoxic environment. 31237014
2020-08-12 12:10:00 The study demonstrates that dysregulated mitochondrial quality control due to defective mitophagy receptor FUNDC1 links with metabolic disorders via MAPK signaling and inflammatory responses. 30898010
2020-06-20 11:07:00 BNIP3L- and FUNDC1-mediated mitophagy is a critical regulator of mitochondrial network formation during differentiation, as well as the consequences of accumulating mtDNA mutations. 30741592
2020-05-23 11:25:00 cascade of events links FUNDC1-regulated mitophagy with inflammasome activation, thus contributing to tumorigenesis 30053328
2019-09-21 10:19:00 results confirmed that CK2alpha serves as a negative regulator of mitochondrial homeostasis via suppression of FUNDC1-required mitophagy, favoring the development of cardiac IR injury. 29540794

名称对应

Type IDs
Synonymous 1500005J14Rik, 1810033P05Rik
Gene
UniProtKB-ID: FUND1_MOUSE, H3BJZ1_MOUSE, H3BJ77_MOUSE
UniprotKB: Q9DB70, H3BJZ1, H3BJ77
UniParc: UPI00001CD580, UPI000154CBBF, UPI0000022503
EMBL: AK005163, AK168868, BC012515, CH466584, BX005345, BC030487
Ensembl: ENSMUSG00000025040
KO: mmu:72018
Nucleutide sequences
EMBL-CDS: BAB23854.1, AAH30487.1, EDL35721.1, AAH12515.1, BAE40687.1
Ensembl_TRS: ENSMUST00000026016, ENSMUST00000176638, ENSMUST00000142638, ENSMUST00000177213
Protein sequencees
Ensembl_PRO: ENSMUSP00000026016, ENSMUSP00000135183, ENSMUSP00000134878, ENSMUSP00000135026
RefSeq: XP_011245798.1, NP_001300675.1, NP_082334.1, NP_001300674.1
Others
UniRef100: UniRef100_H3BJZ1, UniRef100_Q9DB70
UniRef90: UniRef90_Q9DB70, UniRef90_H3BJZ1
UniRef50: UniRef50_Q9DB70, UniRef50_A0A5N3XG63
UniGene: Mm.41558
CCDS: CCDS30035.1

全选

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