Ercc8 - excision repaiross-complementing rodent repair deficiency, complementation group 8-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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71991 Ercc8

基因描述

Type	Description
Definition	excision repaiross-complementing rodent repair deficiency, complementation group 8

研究结论

Date	Results	Publications
2015-05-09 11:44:00	This study demonistrated that Cockayne syndrome group A deficiencies predispose to hearing loss and cochlear hair cell degeneration in mice.	25762674
2010-09-27 11:04:00	MtDNA mutations are highly increased in cells from subcutaneous fat of aged Csa(-/-) mice	20100872
2010-01-21 00:00:00	difference in oxidative DNA damage sensitivity between CSA- and CSB-deficient cell lines and mice	15340056

名称对应

Type	IDs
Synonymous	2410022P04Rik, 2810431L23Rik, 4631412O06Rik, B130065P18Rik, Ckn1, Csa
Gene	UniProtKB-ID: ERCC8_MOUSE UniprotKB: Q8CFD5 UniParc: UPI0000028B20 EMBL: AK010576, AK157175, BC037200, AJ427222 Ensembl: ENSMUSG00000021694 KO: mmu:71991
Nucleutide sequences	EMBL-CDS: BAB27039.1, AAH37200.1, BAE33989.1, CAD20255.1 Ensembl_TRS: ENSMUST00000054835
Protein sequencees	Ensembl_PRO: ENSMUSP00000059211 RefSeq: NP_001349332.1, XP_017171097.1, NP_082318.2
Others	UniRef100: UniRef100_Q8CFD5 UniRef90: UniRef90_Q8CFD5 UniRef50: UniRef50_Q13216 UniGene: Mm.212208 CCDS: CCDS26761.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
27122034	Mutations in Cockayne Syndrome-Associated Genes (Csa and Csb) Predispose to Cisplatin-Induced Hearing Loss in Mice. J Neurosci Robert N Rainey , Sum-Yan Ng , Juan Llamas , Gijsbertus T J van der Horst , Neil Segil	2016-04-27	-
25762674	Cockayne syndrome group B (Csb) and group a (Csa) deficiencies predispose to hearing loss and cochlear hair cell degeneration in mice. J. Neurosci. A Paul Nagtegaal , Robert N Rainey , Ingrid van der Pluijm , Renata M C Brandt , Gijsbertus T J van der Horst , J Gerard G Borst , Neil Segil	2015-03-11	Cdh23, Ercc6, Ercc8
22174697	Age-related neuronal degeneration: complementary roles of nucleotide excision repair and transcription-coupled repair in preventing neuropathology. PLoS Genet. Dick Jaarsma , Ingrid van der Pluijm , Monique C de Waard , Elize D Haasdijk , Renata Brandt , Marcel Vermeij , Yvonne Rijksen , Alex Maas , Harry van Steeg , Jan H J Hoeijmakers , Gijsbertus T J van der Horst	2011-12-01	-
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
21267068	A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. Graciana Diez-Roux , Sandro Banfi , Marc Sultan , Lars Geffers , Santosh Anand , David Rozado , Alon Magen , Elena Canidio , Massimiliano Pagani , Ivana Peluso , Nathalie Lin-Marq , Muriel Koch , Marchesa Bilio , Immacolata Cantiello , Roberta Verde , Cristian De Masi , Salvatore A Bianchi , Juliette Cicchini , Elodie Perroud , Shprese Mehmeti , Emilie Dagand , Sabine Schrinner , Asja NÃ¼rnberger , Katja Schmidt , Katja Metz , Christina Zwingmann , Norbert Brieske , Cindy Springer , Ana Martinez Hernandez , Sarah Herzog , Frauke Grabbe , Cornelia Sieverding , Barbara Fischer , Kathrin Schrader , Maren Brockmeyer , Sarah Dettmer , Christin Helbig , Violaine Alunni , Marie-Annick Battaini , Carole Mura , Charlotte N Henrichsen , Raquel Garcia-Lopez , Diego Echevarria , Eduardo Puelles , Elena Garcia-Calero , Stefan Kruse , Markus Uhr , Christine Kauck , Guangjie Feng , Nestor Milyaev , Chuang Kee Ong , Lalit Kumar , MeiSze Lam , Colin A Semple , Attila Gyenesei , Stefan Mundlos , Uwe Radelof , Hans Lehrach , Paolo Sarmientos , Alexandre Reymond , Duncan R Davidson , Pascal DollÃ© , Stylianos E Antonarakis , Marie-Laure Yaspo , Salvador Martinez , Richard A Baldock , Gregor Eichele , Andrea Ballabio	2011-01-18	-
20211142	An atlas of combinatorial transcriptional regulation in mouse and man. Cell Timothy Ravasi , Harukazu Suzuki , Carlo Vittorio Cannistraci , Shintaro Katayama , Vladimir B Bajic , Kai Tan , Altuna Akalin , Sebastian Schmeier , Mutsumi Kanamori-Katayama , Nicolas Bertin , Piero Carninci , Carsten O Daub , Alistair R R Forrest , Julian Gough , Sean Grimmond , Jung-Hoon Han , Takehiro Hashimoto , Winston Hide , Oliver Hofmann , Atanas Kamburov , Mandeep Kaur , Hideya Kawaji , Atsutaka Kubosaki , Timo Lassmann , Erik van Nimwegen , Cameron Ross MacPherson , Chihiro Ogawa , Aleksandar Radovanovic , Ariel Schwartz , Rohan D Teasdale , Jesper TegnÃ©r , Boris Lenhard , Sarah A Teichmann , Takahiro Arakawa , Noriko Ninomiya , Kayoko Murakami , Michihira Tagami , Shiro Fukuda , Kengo Imamura , Chikatoshi Kai , Ryoko Ishihara , Yayoi Kitazume , Jun Kawai , David A Hume , Trey Ideker , Yoshihide Hayashizaki	2010-03-05	-
20100872	Proteins of nucleotide and base excision repair pathways interact in mitochondria to protect from loss of subcutaneous fat, a hallmark of aging. J Exp Med York Kamenisch , Maria Fousteri , Jennifer Knoch , Anna-Katharina von Thaler , Birgit Fehrenbacher , Hiroki Kato , Thomas Becker , Martijn E T DollÃ© , Raoul Kuiper , Marc Majora , Martin Schaller , Gijsbertus T J van der Horst , Harry van Steeg , Martin RÃ¶cken , Doron Rapaport , Jean Krutmann , Leon H Mullenders , Mark Berneburg	2010-02-15	-
20059953	A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell Shigetoshi Yokoyama , Yoshiaki Ito , Hiroe Ueno-Kudoh , Hirohito Shimizu , Kenta Uchibe , Sonia Albini , Kazuhiko Mitsuoka , Shigeru Miyaki , Minako Kiso , Akane Nagai , Tomohiro Hikata , Tadahiro Osada , Noritsugu Fukuda , Satoshi Yamashita , Daisuke Harada , Valeria Mezzano , Masataka Kasai , Pier Lorenzo Puri , Yoshihide Hayashizaki , Haruo Okado , Megumi Hashimoto , Hiroshi Asahara	2009-12-01	-
18799693	Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. Gwenn M Hansen , Diane C Markesich , Michael B Burnett , Qichao Zhu , Karen M Dionne , Lizabeth J Richter , Richard H Finnell , Arthur T Sands , Brian P Zambrowicz , Alejandro Abuin	2008-10-01	Gm11335, Gm17762, A930017K11Rik, BC028777, Gm13999, Gm11696, Gm12359, Gm10589, D030047H15Rik, Gm10856, Gm10685, Gm10062, Gm10433, Gm10648, Gm10840, Gm15441, Gm10684, Gm9900, Gm10822, Gm10687, Gm11744, Gm10747, Arih2os, B230344G16Rik, Fmr1os, Tmem51os1, Gm14488, Gm13033, Gm10789, Gm10615, Gm1976, Gm9967, Gm9917, Gm1974, Gm11496, Gm13580, Gm2085, Gm2183, Gm2245, Tbx3os1, Gm12980, Gm2329, Lncenc1, Gm2381, Snhg12, Gm2479, Gm12942, Gm2529, Gm2533, Rpl30-ps7, Rsf1os2, Gm2695, 2810416G20Rik, Rpl30-ps6, Gm2773, Gm2788, Dynlt1f, Gm9793, Gm2885, Gm2920, Gm15506, Gm11627, Gm10518, Gm13496, Gm3134, Gm12827, Gm3143, Gm10144, Ahnak2, Gm3196, Gm13242, Gm3325, Gm13247, Gm10863, Gm13157, 4930522L14Rik, Gm3552, Gm15226, Gm3604, Gm3643, BC005561, Gm3716, 2810410L24Rik, Gm10282, Gm3839, Nhsl2, 4732419C18Rik, Gm3906, Gm3973, Gm4013, Apol7d, Gm12057, Gm10489, Rex2, 1110002L01Rik, Gm4189, Gm4204, 4632428C04Rik, 9130023H24Rik
17145777	Retinal degeneration and ionizing radiation hypersensitivity in a mouse model for Cockayne syndrome. Mol. Cell. Biol. Theo G M F Gorgels , Ingrid van der Pluijm , Renata M C Brandt , George A Garinis , Harry van Steeg , Gerard van den Aardweg , Gerard H Jansen , Jan M Ruijter , Arthur A B Bergen , Dirk van Norren , Jan H J Hoeijmakers , Gijsbertus T J van der Horst	2007-02-01	Ercc6, Ercc8, Ercc8

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