| Type | Description |
|---|---|
| Definition | protein arginine N-methyltransferase 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-18 12:14:00 | PRMT3 is an essential regulator of mesenchymal stem cell-mediated osteogenesis and bone homeostasis. | 31378783 |
| 2020-02-08 10:30:00 | Inhibition of PRMT3 activity reduces hepatic steatosis without altering atherosclerosis susceptibility in apoE knockout mice. | 30776415 |
| 2019-09-28 11:13:00 | We have shown that PRMT3 acts as a specific co-activator for LXR-induced hepatic lipogenesis in vivo. Short-term combination treatment with the LXR agonist T0901317 and the PRMT3 inhibitor SGC707 is associated with a beneficial gene expression profile, that is, increased macrophage cholesterol efflux transcription with only limited hepatic lipogenesis gene induction. | 29774529 |
| 2015-03-21 10:55:00 | PRMT3 translocation by palmitic acid is coupled to the binding of LXRalpha, which is responsible for the onset of fatty liver. | 25187371 |
| 2010-01-21 00:00:00 | The present ontogenetic analysis of PRMT1 and PRMT3 using Western blot methodology clearly revealed that PRMT3 develops during the perinatal stage and its expression is maintained even in adulthood. | 16797132 |
| Type | IDs |
|---|---|
| Synonymous | 2010005E20Rik, 2410018A17Rik, AL033309, Hrmt1l3 |
| Gene |
UniProtKB-ID:
ANM3_MOUSE
UniprotKB:
Q922H1
UniParc:
UPI000018CE07,
UPI00000EBA9F
EMBL:
AY151050,
AK086646,
BC008128,
AK031738,
BC050775
Ensembl:
ENSMUSG00000030505
KO:
mmu:71974
|
| Nucleutide sequences |
EMBL-CDS:
AAH50775.1,
AAH08128.1,
AAN84530.1,
BAC27531.1,
BAC39708.1
Ensembl_TRS:
ENSMUST00000032715
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000032715
RefSeq:
NP_598501.1
|
| Others |
UniRef100:
UniRef100_Q922H1
UniRef90:
UniRef90_O70467
UniRef50:
UniRef50_O70467
UniGene:
Mm.33202,
Mm.349442
CCDS:
CCDS21307.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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