| Type | Description |
|---|---|
| Definition | NADPH oxidase organizer 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-10-13 12:02:00 | production stimulated by NoxO1 and p47phox limit endothelium-dependent relaxation and maintain blood pressure in mice. However, NoxO1 and p47phox cannot substitute each other despite their similar effect on vascular function. Deletion of NoxO1 induced an anti-inflammatory phenotype, whereas p47phox deletion rather elicited a hyper-inflammatory response. | 29195137 |
| 2017-06-24 11:15:00 | NoxO1 stimulates alpha-secretase activity probably through reactive oxygen species-mediated oxidation. Deletion of NoxO1 attenuates Notch signaling and thereby promotes a tip-cell phenotype that results in increased angiogenesis. | 27283741 |
| 2014-05-17 13:24:00 | Genetic susceptibility to alcoholic steatohepatitis was linked to two candidate genes, Noxo1 (and Nlrc4). | 23763294 |
| 2010-09-13 11:29:00 | The first quantitative characterization of the interactions made between the cytosolic regulators NOXO1 and NOXA1 and membrane-bound p22(phox), is presented. | 20454568 |
| 2010-01-21 00:00:00 | role in activating superoxide generation by the NADPH oxidase NOX1 | 12473664 |
| Type | IDs |
|---|---|
| Synonymous | 2310034C04Rik, P41NOX, P41NOXA, P41NOXB, P41NOXC, Snx28, hslt |
| Gene |
UniProtKB-ID:
NOXO1_MOUSE
UniprotKB:
Q8VCM2
UniParc:
UPI00000216BB,
UPI00000EB979
EMBL:
AF399754,
BC019525,
AK088226,
AF539797,
AK157993,
AK009605
Ensembl:
ENSMUSG00000019320
KO:
mmu:71893
|
| Nucleutide sequences |
EMBL-CDS:
AAK94017.1,
AAN75142.1,
BAB26387.1,
BAE34305.1,
AAH19525.1,
BAC40222.1
Ensembl_TRS:
ENSMUST00000019464
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000019464
RefSeq:
XP_006525014.1,
NP_001344765.1,
XP_017173141.1,
NP_082264.2,
XP_011244932.1
|
| Others |
UniRef100:
UniRef100_Q8VCM2
UniRef90:
UniRef90_Q8VCM2
UniRef50:
UniRef50_Q8VCM2
UniGene:
Mm.390971
CCDS:
CCDS50018.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员