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71890 Mad2l2

71890

Mad2l2

MAD2 mitotic arrest deficient-like 2

protein-coding

Mus musculus

基因描述

Type Description
Definition MAD2 mitotic arrest deficient-like 2

研究结论

Date Results Publications
2020-11-28 13:14:00 MAD2B contributes to parietal epithelial cell activation and crescentic glomerulonephritis via Skp2. 32830536
2020-08-22 15:28:00 REV7 is required for processing AID initiated DNA lesions in activated B cells. 32499490
2019-01-19 12:16:00 53BP1 pathway therefore comprises distinct double-strand break repair activities within chromatin and single-stranded DNA compartments, which explains both the immunological differences between 53bp1- and Rev7- deficient mice and the context specificity of the pathway 30046110
2017-12-30 13:02:00 Skp2, a confirmed APC/C-CDH1 substrate and E-cadherin destroyer, was increased in TGF-beta1-treated proximal tubular epithelial cells, which could be blocked by MAD2B depletion. 27488450
2017-05-20 11:55:00 This study demonstrates using super-resolution microscopy that numerous MAD2L2 microfoci are exclusively associated with euchromatin, similar to other factors of the DNA damage response. In the absence of MAD2L2 the amount of heterochromatin demarcated by H3K9me2 was significantly increased. 28330620

名称对应

Type IDs
Synonymous 2310033C13Rik, G1-453-4, MAD2B, REV7, repro22
Gene
UniProtKB-ID: MD2L2_MOUSE, A2A7G7_MOUSE
UniprotKB: Q9D752, A2A7G7
UniParc: UPI0000023082, UPI000059E21D
EMBL: BC011282, AK150216, AK009587, BC071264, AK165627, AL606929
Ensembl: ENSMUSG00000029003
KO: mmu:71890
Nucleutide sequences
EMBL-CDS: BAE38303.1, AAH71264.1, AAH11282.1, BAB26376.1, BAE29386.1
Ensembl_TRS: ENSMUST00000030860, ENSMUST00000084129, ENSMUST00000105707
Protein sequencees
Ensembl_PRO: ENSMUSP00000030860, ENSMUSP00000081146, ENSMUSP00000101332
RefSeq: XP_006539250.1, XP_030109659.1, XP_030109649.1, XP_006539251.1, XP_030109655.1, XP_006539252.1, XP_030109657.1, NP_001292349.1, XP_006539249.1, XP_030109654.1, XP_030109653.1, XP_006539246.1, XP_030109658.1, XP_030109656.1, XP_030109648.1, NP_082261.2, XP_030109651.1, XP_030109650.1, XP_030109652.1
Others
UniRef100: UniRef100_A2A7G7, UniRef100_Q9D752
UniRef90: UniRef90_A2A7G7, UniRef90_Q9UI95
UniRef50: UniRef50_A0A553PXE6, UniRef50_Q9UI95
UniGene: Mm.9648
CCDS: CCDS18932.1

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