Type | Description |
---|---|
Definition | chitinase 1 (chitotriosidase) |
Date | Results | Publications |
---|---|---|
2021-04-17 13:17:00 | Comparative functional analysis between human and mouse chitotriosidase: Substitution at amino acid 218 modulates the chitinolytic and transglycosylation activity. | 32853624 |
2019-07-06 11:35:00 | these data show a detrimental role of chit1 in Klebsiella pneumoniae lung infections | 29891554 |
2015-12-19 10:23:00 | No significant differences were observed between experimental autoimmune encephalitis and control groups for CHIT-1 expression. | 26079949 |
2013-10-26 11:06:00 | CHIT1 exerts protective effects against atherosclerosis by suppressing inflammatory responses and polarizing macrophages toward an M2 phenotype, and promoting lipid uptake and cholesterol efflux in macrophages. | 23685110 |
Type | IDs |
---|---|
Synonymous | 2300002L19Rik |
Gene |
UniProtKB-ID:
CHIT1_MOUSE,
B2RS82_MOUSE
UniprotKB:
Q9D7Q1,
B2RS82
UniParc:
UPI00001E2EA7,
UPI00000228EA
EMBL:
AY536287,
BC138765,
AK009012,
AY458654
Ensembl:
ENSMUSG00000026450
KO:
mmu:71884
|
Nucleutide sequences |
EMBL-CDS:
AAR14312.1,
BAB26025.1,
AAS47832.1,
AAI38766.1
Ensembl_TRS:
ENSMUST00000086475,
ENSMUST00000159963,
ENSMUST00000160060
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000123979,
ENSMUSP00000124331,
ENSMUSP00000083666
RefSeq:
NP_001271454.1,
XP_006529942.1,
NP_001271453.1,
XP_006529944.1,
XP_006529943.1,
NP_082255.1
|
Others |
UniRef100:
UniRef100_Q9D7Q1
UniRef90:
UniRef90_Q9D7Q1
UniRef50:
UniRef50_Q13231
UniGene:
Mm.328268
CCDS:
CCDS69943.1,
CCDS15304.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
---|---|---|---|
32853624 |
Int J Biol Macromol Masahiro Kimura , Takashi Watanabe , Kazutaka Sekine , Hitomi Ishizuka , Aoi Ikejiri , Masayoshi Sakaguchi , Minori Kamaya , Daisuke Yamanaka , Vaclav Matoska , Peter O Bauer , Fumitaka Oyama |
2020-12-01 | - |
29891554 |
Regulation and Role of Chitotriosidase during Lung Infection with Klebsiella pneumoniae. J. Immunol. Lokesh Sharma , Alyssa K Amick , Swathy Vasudevan , Sei Won Lee , Chad R Marion , Wei Liu , Virginia Brady , Ashley Losier , Santos D Bermejo , Clemente J Britto , Chun Geun Lee , Jack A Elias , Charles S Dela Cruz |
2018-07-15 | - |
26079949 |
Clin. Immunol. Ester Cantó , Carmen Espejo , Carme Costa , Xavier Montalban , Manuel Comabella |
2015-10-01 |
Chil1,
Chil3,
Chit1,
Chia1
|
25764512 |
PLoS Pathog. Darin L Wiesner , Charles A Specht , Chrono K Lee , Kyle D Smith , Liliane Mukaremera , S Thera Lee , Chun G Lee , Jack A Elias , Judith N Nielsen , David R Boulware , Paul R Bohjanen , Marc K Jenkins , Stuart M Levitz , Kirsten Nielsen |
2015-03-01 | - |
23685110 |
Chitinase inhibition promotes atherosclerosis in hyperlipidemic mice. Am. J. Pathol. Shiro Kitamoto , Kensuke Egashira , Toshihiro Ichiki , Xinbing Han , Sara McCurdy , Shohei Sakuda , Kenji Sunagawa , William A Boisvert |
2013-07-01 |
Apoe,
Chit1
|
22826322 |
J. Immunol. Chun Geun Lee , Erica L Herzog , Farida Ahangari , Yang Zhou , Mridu Gulati , Chang-Min Lee , Xueyan Peng , Carol Feghali-Bostwick , Sergio A Jimenez , John Varga , Jack A Elias |
2012-09-01 |
Tgfb1,
Chit1,
CHIT1
|
21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
15923370 |
Marked differences in tissue-specific expression of chitinases in mouse and man. J. Histochem. Cytochem. Rolf G Boot , Anton P Bussink , Marri Verhoek , Piet A J de Boer , Antoon F M Moorman , Johannes M F G Aerts |
2005-10-01 |
Chit1
|
16141072 |
The transcriptional landscape of the mammalian genome. Science P Carninci , T Kasukawa , S Katayama , J Gough , M C Frith , N Maeda , R Oyama , T Ravasi , B Lenhard , C Wells , R Kodzius , K Shimokawa , V B Bajic , S E Brenner , S Batalov , A R R Forrest , M Zavolan , M J Davis , L G Wilming , V Aidinis , J E Allen , A Ambesi-Impiombato , R Apweiler , R N Aturaliya , T L Bailey , M Bansal , L Baxter , K W Beisel , T Bersano , H Bono , A M Chalk , K P Chiu , V Choudhary , A Christoffels , D R Clutterbuck , M L Crowe , E Dalla , B P Dalrymple , B de Bono , G Della Gatta , D di Bernardo , T Down , P Engstrom , M Fagiolini , G Faulkner , C F Fletcher , T Fukushima , M Furuno , S Futaki , M Gariboldi , P Georgii-Hemming , T R Gingeras , T Gojobori , R E Green , S Gustincich , M Harbers , Y Hayashi , T K Hensch , N Hirokawa , D Hill , L Huminiecki , M Iacono , K Ikeo , A Iwama , T Ishikawa , M Jakt , A Kanapin , M Katoh , Y Kawasawa , J Kelso , H Kitamura , H Kitano , G Kollias , S P T Krishnan , A Kruger , S K Kummerfeld , I V Kurochkin , L F Lareau , D Lazarevic , L Lipovich , J Liu , S Liuni , S McWilliam , M Madan Babu , M Madera , L Marchionni , H Matsuda , S Matsuzawa , H Miki , F Mignone , S Miyake , K Morris , S Mottagui-Tabar , N Mulder , N Nakano , H Nakauchi , P Ng , R Nilsson , S Nishiguchi , S Nishikawa , F Nori , O Ohara , Y Okazaki , V Orlando , K C Pang , W J Pavan , G Pavesi , G Pesole , N Petrovsky , S Piazza , J Reed , J F Reid , B Z Ring , M Ringwald , B Rost , Y Ruan , S L Salzberg , A Sandelin , C Schneider , C Schönbach , K Sekiguchi , C A M Semple , S Seno , L Sessa , Y Sheng , Y Shibata , H Shimada , K Shimada , D Silva , B Sinclair , S Sperling , E Stupka , K Sugiura , R Sultana , Y Takenaka , K Taki , K Tammoja , S L Tan , S Tang , M S Taylor , J Tegner , S A Teichmann , H R Ueda , E van Nimwegen , R Verardo , C L Wei , K Yagi , H Yamanishi , E Zabarovsky , S Zhu , A Zimmer , W Hide , C Bult , S M Grimmond , R D Teasdale , E T Liu , V Brusic , J Quackenbush , C Wahlestedt , J S Mattick , D A Hume , C Kai , D Sasaki , Y Tomaru , S Fukuda , M Kanamori-Katayama , M Suzuki , J Aoki , T Arakawa , J Iida , K Imamura , M Itoh , T Kato , H Kawaji , N Kawagashira , T Kawashima , M Kojima , S Kondo , H Konno , K Nakano , N Ninomiya , T Nishio , M Okada , C Plessy , K Shibata , T Shiraki , S Suzuki , M Tagami , K Waki , A Watahiki , Y Okamura-Oho , H Suzuki , J Kawai , Y Hayashizaki , FANTOM Consortium , RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) |
2005-09-02 | - |
16141073 |
Antisense transcription in the mammalian transcriptome. Science S Katayama , Y Tomaru , T Kasukawa , K Waki , M Nakanishi , M Nakamura , H Nishida , C C Yap , M Suzuki , J Kawai , H Suzuki , P Carninci , Y Hayashizaki , C Wells , M Frith , T Ravasi , K C Pang , J Hallinan , J Mattick , D A Hume , L Lipovich , S Batalov , P G Engström , Y Mizuno , M A Faghihi , A Sandelin , A M Chalk , S Mottagui-Tabar , Z Liang , B Lenhard , C Wahlestedt , RIKEN Genome Exploration Research Group , Genome Science Group (Genome Network Project Core Group) , FANTOM Consortium |
2005-09-02 |
Gm14018,
Gm14964,
F630206G17Rik,
Oog3,
Notumos,
Ldlrap1,
Mdn1,
Pydc3,
9330171B17Rik,
Mfap1b,
Tmsb15b2,
Gm12802,
E430020m11rik,
Gm11335,
Gm15772,
Gm17762,
A930017K11Rik,
LOC100036513,
Gata5os,
Umad1,
Gm16982,
Gm9887,
Gm9872,
LOC100036530,
Gm9934,
Gm9913,
Gm11149,
BC028777,
Gm13999,
LOC100036540,
Gm9744,
Gm9983,
D630002J18Rik,
Gm16525,
Gm11696,
Dnajc3,
9430060I03Rik,
Gm12359,
4921516A02Rik,
Fam129c,
Gm10589,
Rsph3b,
Rnaset2a,
5430403G19Rik,
D030047H15Rik,
Gm13274,
B930046K06Rik,
Gm10862,
Gm10792,
Gm10802,
Gm10532,
G730003C15Rik,
Runx2os1,
Gm15612,
Gm10856,
Gm10857,
Gm10685,
Gm10803,
Gm10723,
F630028O10Rik,
Gm10836,
Gm10405,
Gm10513,
Gm10609,
F630201L12Rik,
4932427H20Rik,
Zfp389,
Gm10763,
Gm10062,
Gm10714,
Gm10531,
Gm10876,
Gm10750,
Gm10433,
Gm10837,
Gm10647,
Gm10648,
Gm10650,
Gm10610,
F830115B05Rik,
Gm10473,
Gm10614,
Gm10286,
G730046D07Rik,
Gm10287,
Gm10785,
Gm10183,
Gm10512,
1700061E17Rik,
Gm44113,
Gm10579,
Gm10741,
Gm10827,
Gm10522,
Gm10536,
Gm15998,
Faddos,
D130050E23Rik,
Gm10735
|
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