| Type | Description |
|---|---|
| Definition | DDB1 and CUL4 associated factor 7 |
| Date | Results | Publications |
|---|---|---|
| 2019-11-23 11:02:00 | We show that active DYRK1A exists in a complex with the WD40-repeat protein DCAF7 that stabilizes and tethers DYRK1A to Pol II, so that DYRK1A-DCAF7 can co-migrate with and phosphorylate Pol II along the myogenic gene loci. Thus, DCAF7 modulates the kinase signaling output of DYRK1A on Pol II to stimulate myogenic transcription after active P-TEFb function is shut off. | 30864669 |
| 2018-04-28 10:43:00 | Depleting Huntingtin-associated protein 1 (Hap1) promoted the dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A)-DDB1 and CUL4 associated factor 7 (Dcaf7) interaction and increased the DYRK1A protein level. | 28137862 |
| Type | IDs |
|---|---|
| Synonymous | 1700012F10Rik, 2610037L01Rik, C86529, HAN11, Wdr68 |
| Gene |
UniProtKB-ID:
DCAF7_MOUSE,
Q80ZU1_MOUSE
UniprotKB:
P61963,
Q80ZU1
UniParc:
UPI000000BC65,
UPI0000004087
EMBL:
AK165674,
AK005902,
BC048722,
AK047435,
BC048165
Ensembl:
ENSMUSG00000049354
KO:
mmu:71833
|
| Nucleutide sequences |
EMBL-CDS:
BAC33058.1,
BAE38331.1,
BAB24308.1,
AAH48722.1,
AAH48165.1
Ensembl_TRS:
ENSMUST00000058438
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000058168
RefSeq:
NP_082222.1
|
| Others |
UniRef100:
UniRef100_Q80ZU1,
UniRef100_P61962
UniRef90:
UniRef90_P61962,
UniRef90_F6PSI0
UniRef50:
UniRef50_P61962,
UniRef50_F6PSI0
UniGene:
Mm.307455
CCDS:
CCDS25546.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员