| Type | Description |
|---|---|
| Definition | cysteine rich secretory protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-02-02 10:42:00 | The integrated network analysis identified BRCA1 and CRISP2 differentially methylated regions (DMR) as the most central disease-associated DNA methylation biomarkers. Moreover, methylation changes at BRCA1 and CRISP2 specific CpG sites were consistently associated with subclinical atherosclerosis measures. | 28698603 |
| 2018-05-05 11:48:00 | low expression of CRISP2 protein rather than its mRNA was observed in the ejaculated spermatozoa from asthenoteratozoospermic patients as compared with normozoospermic males | 27517483 |
| 2017-03-04 10:07:00 | Results identified CRISP2 as a potential binding protein of PSP94 from human sperm. | 27161017 |
| 2016-12-17 12:06:00 | Crisp2 genetic defects in sperm from humans and mice result in male infertility. | 26786179 |
| 2015-09-12 11:31:00 | Preliminary insight into the mechanism leading to the reduced CRISP2 expression in asthenozoospermia, offering a potential therapeutic target for treating male infertility or for male contraception. | 25505194 |
| Type | IDs |
|---|---|
| Synonymous | CRISP-2, CT36, GAPDL5, TPX1, TSP1 |
| Gene |
UniProtKB-ID:
CRIS2_HUMAN,
A0A024RD74_HUMAN
UniprotKB:
P16562,
A0A024RD74
UniParc:
UPI000013728C,
UPI00001A388D
EMBL:
AK223337,
HM005356,
AY292862,
BC022011,
CH471081,
M25532,
AY773479,
X95239,
AY289796,
AY292863,
AK292385,
AL121950,
BC107707
Ensembl:
ENSG00000124490
KO:
hsa:7180
|
| Nucleutide sequences |
EMBL-CDS:
AAP44113.1,
AAA61220.1,
CAA64526.1,
AAP41200.1,
BAF85074.1,
AAH22011.1,
AAI07708.1,
AAV48552.1,
BAD97057.1,
EAX04345.1,
AAP44114.1,
EAX04340.1,
AEE60956.1,
EAX04342.1,
EAX04344.1,
EAX04347.1,
EAX04343.1,
EAX04346.1,
EAX04341.1
Gene_ORFName:
hCG_21701
Ensembl_TRS:
ENST00000339139,
ENST00000618917,
ENST00000616725
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000339155,
ENSP00000482890,
ENSP00000484609
RefSeq:
XP_011513144.1,
NP_001135880.1,
NP_001135889.1,
NP_003287.1,
XP_005249410.1,
NP_001135907.1,
XP_005249409.1,
XP_005249413.1,
XP_005249407.1,
NP_001135879.1,
NP_001248751.1,
XP_011513145.1,
XP_011513143.1,
XP_005249408.1,
XP_005249406.1
|
| Others |
UniRef100:
UniRef100_P16562
UniRef90:
UniRef90_P16562
UniRef50:
UniRef50_P16562
UniGene:
Hs.2042
CCDS:
CCDS4928.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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