| Type | Description |
|---|---|
| Definition | platelet-derived growth factor, D polypeptide |
| Date | Results | Publications |
|---|---|---|
| 2018-07-28 11:40:00 | Data (including data from studies using transgenic/mutant mice and cells from such mice) suggest that Pdgfd promotes cell proliferation, cell migration, and expression of inflammatory factors in adventitial fibroblasts; in obese mice, inhibition of Pdgfd significantly reduces aortic aneurysm formation (induced by infusion of angiotensin II). | 29794241 |
| 2017-02-04 12:33:00 | upregulated in kidney fibrosis, may mediate renal scarring, and is dispensable for normal kidney development and physiological functions | 26924050 |
| 2016-08-13 12:18:00 | Inactivation of the Pdgfd gene resulted in a mild phenotype in C57BL/6 mice, and the offspring was viable, fertile and generally in good health. | 27032083 |
| 2015-07-25 10:27:00 | PDGF-D intensifies fibrogenesis by interfering with the fibrolytic activity of the TIMP-1/MMP-2/MMP-9 system, and PDGF-D signaling is mediated through both PDGF-alpha and -beta receptors. | 25576870 |
| 2014-12-20 10:47:00 | Radial glia require PDGFD-PDGFRbeta signalling in human but not mouse neocortex | 25391964 |
| Type | IDs |
|---|---|
| Synonymous | 1110003I09Rik |
| Gene |
UniProtKB-ID:
PDGFD_MOUSE
UniprotKB:
Q925I7
UniParc:
UPI00000291AD,
UPI00005AC088,
UPI000003C75B
EMBL:
BC030896,
AF335583,
AK003359,
AK141551
Ensembl:
ENSMUSG00000032006
KO:
mmu:71785
|
| Nucleutide sequences |
EMBL-CDS:
BAB22735.2,
AAH30896.1,
BAE24732.1,
AAK38839.1
Ensembl_TRS:
ENSMUST00000168039,
ENSMUST00000058692,
ENSMUST00000214892
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000056240,
ENSMUSP00000149162,
ENSMUSP00000128388
RefSeq:
NP_001344326.1,
XP_036011196.1,
XP_011240672.1,
NP_001344327.1,
NP_082200.1,
XP_006509950.1,
XP_036011197.1
|
| Others |
UniRef100:
UniRef100_Q925I7
UniRef90:
UniRef90_Q9EQT1
UniRef50:
UniRef50_Q9EQT1
UniGene:
Mm.390122
CCDS:
CCDS22801.1,
CCDS90489.1,
CCDS90490.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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