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7175 TPR

7175

TPR

translocated promoter region, nuclear basket protein

protein-coding

Homo sapiens

基因描述

Type Description
Definition translocated promoter region, nuclear basket protein

研究结论

Date Results Publications
2021-02-06 13:51:00 TPR is required for the efficient nuclear export of mRNAs and lncRNAs from short and intron-poor genes. 33091126
2019-05-25 10:58:00 TPR contributes to the organization of the nuclear lamina and in cooperation with lamin B1 and lamin A-C guards the interphase assembly of nuclear pore complexes. 30762072
2019-03-02 12:14:00 TPR is necessary for both formation and maintenance of senescence-associated heterochromatin foci 30692205
2018-03-24 10:11:00 Fusion of TPR(2-142) protein to the MET intracellular domain strongly and selectively stabilizes the alphaG helix of the MET kinase domain.TPR has an ability to induce dimerization and activation of fusion kinases. 28528776
2018-03-10 11:37:00 Using a BioID proximity-based proteomic screen, we identify the nuclear pore complex protein TPR as a novel AKAP95 binding partner. We show interaction between AKAP95 and TPR in mitosis, and an AKAP95-dependent enrichment of TPR in the spindle microtubule area in metaphase, then later in the spindle midzone area. 28379780

名称对应

Type IDs
Gene
UniProtKB-ID: TPR_HUMAN
UniprotKB: P12270
UniParc: UPI000046FCF4, UPI0000062253
EMBL: X66397, AL133553, X63105, CH471067, AL596220, X62947, U69668, Y00672
Ensembl: ENSG00000047410
KO: hsa:7175
Nucleutide sequences
EMBL-CDS: CAA68681.1, AAB48030.1, CAA44719.1, CAA44819.1, EAW91205.1, CAA47021.1
Ensembl_TRS: ENST00000613151, ENST00000367478
Protein sequencees
Ensembl_PRO: ENSP00000483425, ENSP00000356448
RefSeq: NP_003283.2
Others
UniRef100: UniRef100_P12270
UniRef90: UniRef90_P12270
UniRef50: UniRef50_P12270
UniGene: Hs.279640
CCDS: CCDS41446.1

全选

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