| Type | Description |
|---|---|
| Definition | single-strand selective monofunctional uracil DNA glycosylase |
| Date | Results | Publications |
|---|---|---|
| 2019-02-23 12:35:00 | we showed that SMUG1 efficiently prevent genomic uracil accumulation, even in the presence of UNG, and identified mutational signatures associated with combined UNG and SMUG1 deficiency. | 28775312 |
| 2014-09-13 11:21:00 | Nonetheless, using a highly MSH2-dependent mechanism, Ung(-/-) Smug1(-/-) mice can still produce detectable levels of switched isotypes, especially IgG1 | 24771041 |
| 2012-10-27 11:21:00 | SMUG1 is the dominant glycosylase responsible for 5-hydroxymethyluracil-excision in mice as well as the major UNG-backup for U-excision. | 22447450 |
| 2011-07-16 11:30:00 | analysis of species specific differences between mouse and humans in regulation of SMUG1 and UNG2 | 21454529 |
| 2010-01-21 00:00:00 | The structure and specificity of SMUG1 have been solved. | 12820976 |
| Type | IDs |
|---|---|
| Synonymous | 1200013B09Rik, A930006H09Rik, C85220 |
| Gene |
UniProtKB-ID:
SMUG1_MOUSE
UniprotKB:
Q6P5C5
UniParc:
UPI000002406E
EMBL:
BC062960,
AK004735,
BC050253
Ensembl:
ENSMUSG00000036061
KO:
mmu:71726
|
| Nucleutide sequences |
EMBL-CDS:
BAB23517.1,
AAH50253.1,
AAH62960.1
Ensembl_TRS:
ENSMUST00000064067,
ENSMUST00000229377,
ENSMUST00000229371
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000155594,
ENSMUSP00000065835,
ENSMUSP00000155700
RefSeq:
XP_036015486.1,
NP_082161.2,
XP_036015488.1,
XP_011244033.1,
XP_011244035.1,
XP_011244034.1,
XP_017172241.1,
XP_036015487.1,
XP_006521478.1
|
| Others |
UniRef100:
UniRef100_Q6P5C5
UniRef90:
UniRef90_Q811Q1
UniRef50:
UniRef50_Q53HV7
UniGene:
Mm.254820,
Mm.463445
CCDS:
CCDS27898.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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