| Type | Description |
|---|---|
| Definition | capicua transcriptional repressor |
| Date | Results | Publications |
|---|---|---|
| 2020-06-27 10:32:00 | Derepression of Etv5 increases Hobit expression in Cic -deficient CD8+ T cells and consequently enhances CD8+ T memory cell formation in liver, thereby leading to liver injury. | 30810242 |
| 2019-08-31 10:06:00 | CIC is a transcriptional repressor of genes regulated by MAPK signaling. | 29844126 |
| 2019-06-08 10:54:00 | these results identify Cic as an important regulator of cell fate in neurodevelopment and oligodendroglioma, and suggest that its loss contributes to oligodendroglioma by promoting proliferation and an oligodendrocyte precursor cells -like identity via Ets overactivity. | 31043608 |
| 2018-12-22 10:13:00 | maintains T-cell homeostasis and negatively regulates follicular helper T cell development and autoimmunity | 28855737 |
| 2018-08-04 11:16:00 | Loss of CIC causes T cell lymphoblastic leukemia/lymphoma. | 29382756 |
| Type | IDs |
|---|---|
| Synonymous | 1200010B10Rik, mKIAA0306 |
| Gene |
UniProtKB-ID:
CIC_MOUSE
UniprotKB:
Q924A2
UniParc:
UPI00005B2E75,
UPI0000D8A941
EMBL:
AF363690,
AC156992,
AK004685,
BC058665,
AK147276,
AK147535,
AB093224,
BC040463
Ensembl:
ENSMUSG00000005442
KO:
mmu:71722
|
| Nucleutide sequences |
EMBL-CDS:
BAE27978.1,
AAK73516.1,
BAE27813.1,
AAH40463.1,
BAC41408.1,
AAH58665.1,
BAB23472.1
Ensembl_TRS:
ENSMUST00000169266,
ENSMUST00000163320
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000126659,
ENSMUSP00000132351
RefSeq:
NP_001289740.1,
XP_011248999.1,
XP_006540430.1,
XP_036009335.1,
NP_082158.2,
XP_030098851.1,
XP_017167798.1,
XP_017167799.1,
XP_011248998.1,
XP_036009331.1,
XP_036009332.1,
XP_036009334.1,
XP_036009333.1,
XP_006540431.1
|
| Others |
UniRef100:
UniRef100_Q924A2
UniRef90:
UniRef90_Q924A2
UniRef50:
UniRef50_Q924A2
UniGene:
Mm.28833
CCDS:
CCDS52146.1,
CCDS80678.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员