| Type | Description |
|---|---|
| Definition | MUS81 structure-specific endonuclease subunit |
| Date | Results | Publications |
|---|---|---|
| 2017-09-16 10:54:00 | this study shows that immune rejection of prostate cancer cells relies on Mus81 and STING | 27178469 |
| 2017-09-09 10:05:00 | Our study highlights the importance of the cooperation between Rad54 and Mus81 for mediating DNA DSB repair and restraining chromosome missegregation. | 26876210 |
| 2016-10-22 11:29:00 | Mus81 knockdown improves the chemosensitivity of HCC cells by inducing S-phase arrest and promoting apoptosis through CHK1 pathway, suggesting Mus81 as a novel therapeutic target for HCC. | 26714930 |
| 2014-12-06 11:26:00 | Using mice deficient in both Mus81 and the FA pathway protein FancC, we show both proteins cooperate in parallel pathways, as concomitant loss of FancC and Mus81 triggered cell-type-specific proliferation arrest, apoptosis and DNA damage accumulation in utero. | 25056314 |
| 2014-01-18 10:44:00 | Data indicate that SLX1 and MUS81-EME1 nucleases act together to resolve Holliday junctions (HJs) in a manner that requires tethering to SLX4. | 24076219 |
| Type | IDs |
|---|---|
| Synonymous | 1200008A18Rik, AI182501, AW045863 |
| Gene |
UniProtKB-ID:
MUS81_MOUSE
UniprotKB:
Q91ZJ0
UniParc:
UPI0000022493
EMBL:
AF425647,
BC026560
Ensembl:
ENSMUSG00000024906
KO:
mmu:71711
|
| Nucleutide sequences |
EMBL-CDS:
AAH26560.1,
AAL28066.1
Ensembl_TRS:
ENSMUST00000124334
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000114895
RefSeq:
NP_082153.3
|
| Others |
UniRef100:
UniRef100_Q91ZJ0
UniRef90:
UniRef90_Q91ZJ0
UniRef50:
UniRef50_Q96NY9
UniGene:
Mm.27697
CCDS:
CCDS29467.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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