| Type | Description |
|---|---|
| Definition | tropomyosin 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:13:00 | Upregulation of tropomyosin alpha-4 chain in patients' saliva with oral squamous cell carcinoma as demonstrated by Phage display. | 31804537 |
| 2018-09-29 10:36:00 | TPM4 is associated with clinical progression in colon cancer patients and acts as a tumor suppressor in colon cancer cells. | 29455030 |
| 2018-03-10 11:24:00 | Tpm4.1 is essential to maintain cell-cell adhesions and to inhibit abnormal increases in cell migration and invasion, which are important to prevent invasion and metastasis of breast cancer cells. | 28431393 |
| 2017-09-09 11:49:00 | findings demonstrate a nonredundant role for TPM4 in platelet biogenesis in humans and mice and reveal that truncating variants in TPM4 cause a previously undescribed dominant Mendelian platelet disorder. | 28134622 |
| 2017-08-19 12:38:00 | In diabetes, expression of high molecular weight (HMW) isoforms from tropomyosin 1 (TPM1) were markedly decreased but HMW isoforms from tropomyosin 4 (TPM4) were not significantly different. | 27649540 |
| Type | IDs |
|---|---|
| Synonymous | HEL-S-108 |
| Gene |
UniProtKB-ID:
TPM4_HUMAN,
V9HW56_HUMAN,
K7ENT6_HUMAN,
A0A5F9UN72_HUMAN
UniprotKB:
P67936,
V9HW56,
K7ENT6,
A0A5F9UN72
UniParc:
UPI0000203629,
UPI000002B5B9,
UPI00003D6D7F,
UPI0000001C65
EMBL:
X05276,
CH471106,
BC002827,
AK315076,
BC067225,
AK023385,
BC037576,
AC008894,
BT019634,
M12127,
FJ224305
Ensembl:
ENSG00000167460
KO:
hsa:7171
|
| Nucleutide sequences |
EMBL-CDS:
AAV38440.1,
BAG37545.1,
AAH37576.1,
CAA28888.1,
BAB14554.1,
AAA36774.1,
AAH67225.1,
EAW84521.1,
AAH02827.1,
EAW84523.1,
ACI45997.1,
EAW84524.1
Gene_ORFName:
hCG_1999582,
hCG_1999582
Ensembl_TRS:
ENST00000643579,
ENST00000646974,
ENST00000586833,
ENST00000344824
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000495347,
ENSP00000494125,
ENSP00000467087,
ENSP00000345230
RefSeq:
NP_001354766.1,
XP_024307449.1,
NP_001138632.1,
NP_003281.1,
XP_011526534.1,
NP_001354767.1,
NP_001354765.1,
XP_006722928.1,
XP_016882678.1
|
| Others |
UniRef100:
UniRef100_K7ENT6,
UniRef100_A0A5F9UN72,
UniRef100_P67936
UniRef90:
UniRef90_A0A5F9UN72,
UniRef90_P67936,
UniRef90_A0A2R8YE05
UniRef50:
UniRef50_A0A5F9UN72,
UniRef50_A0A2R8YE05,
UniRef50_P07951-3
UniGene:
Hs.631618
CCDS:
CCDS12338.1,
CCDS46007.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员