例如:"NBL1", "4681", "drought"
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7170 TPM3

7170

TPM3

tropomyosin 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition tropomyosin 3

研究结论

Date Results Publications
2021-04-17 13:14:00 Effects of myopathy-causing mutations R91P and R245G in the TPM3 gene on structural and functional properties of slow skeletal muscle tropomyosin. 33307294
2021-02-20 13:34:00 Regulation of Actin Filament Length by Muscle Isoforms of Tropomyosin and Cofilin. 32560136
2020-07-18 12:15:00 actin's D- and H-loop are the sites involved in regulation of cofilin activity by tropomyosin isoforms 31996302
2020-07-11 11:51:00 It was shown that the Ala155Thr (A155T) mutation increased the Ca(2+)-sensitivity of thin filaments in solution. In the absence of myosin heads in muscle fibres, the mutation did not alter the ability of troponin to switch the thin filaments on and off at high and low Ca(2+), respectively. 31155291
2020-07-11 10:12:00 perturbation of Tpm3.1/3.2 results in decreased myosin IIa in stress fibres, which is consistent with a role for Tpm3.1 in maintaining myosin IIa localisation in stress fibres. 31331962

名称对应

Type IDs
Synonymous CAPM1, CFTD, HEL-189, HEL-S-82p, NEM1, OK/SW-cl.5, TM-5, TM3, TM30, TM30nm, TM5, TPM3nu, TPMsk3, TRK, hscp30
Gene
UniProtKB-ID: TPM3_HUMAN, A0A0S2Z4G4_HUMAN, A0A087WWU8_HUMAN, A0A0S2Z4I4_HUMAN, B4DQ80_HUMAN
UniprotKB: P06753, A0A0S2Z4G4, A0A087WWU8, A0A0S2Z4I4, B4DQ80
UniParc: UPI000002B5B7, UPI0000049FFE, UPI0000458A72, UPI0000000DF4, UPI000013D90D, UPI0000458A76, UPI00017A7977, UPI00005A142F, UPI0000458A75
EMBL: KU178368, DQ120714, BC008407, X04588, AL590431, AF474157, BC072428, CH471121, BC000771, AK298678, KU178370, X04201, BC008425, AY004867, BC015403, X03541
Ensembl: ENSG00000143549
KO: hsa:7170
Nucleutide sequences
EMBL-CDS: CAB37185.1, AAH72428.1, EAW53235.1, ABC40673.1, AAL84570.1, EAW53230.1, AAH08425.1, EAW53229.1, EAW53231.1, AAH00771.1, CAA27798.1, CAA27243.1, AAH08407.1, AAF87083.1, AAH15403.1, ALQ33826.1, ALQ33828.1, BAG60842.1
Ensembl_TRS: ENST00000368531, ENST00000651641, ENST00000323144, ENST00000368533, ENST00000328159, ENST00000341485, ENST00000330188, ENST00000302206, ENST00000611659
Protein sequencees
Ensembl_PRO: ENSP00000357521, ENSP00000357518, ENSP00000357520, ENSP00000357517, ENSP00000341653, ENSP00000307712, ENSP00000339035, ENSP00000498577, ENSP00000480520
RefSeq: NP_001036818.1, NP_705935.1, NP_001036817.1, NP_001351609.1, NP_001351612.1, NP_001265120.1, NP_001265118.1, NP_001265117.1, NP_001351610.1, NP_001265119.1, NP_001351608.1, NP_001351611.1, NP_001336608.1, NP_001036816.1, NP_689476.2
Others
UniRef100: UniRef100_K7BEX0, UniRef100_A0A087WWU8, UniRef100_A0A6J3GT18, UniRef100_P06753, UniRef100_Q5NVF2
UniRef90: UniRef90_A0A384A4R4, UniRef90_A0A087WWU8, UniRef90_K7BEX0, UniRef90_Q5NVF2, UniRef90_P06753
UniRef50: UniRef50_B7Z596, UniRef50_P09493-2, UniRef50_A0A087WWU8, UniRef50_D3Z2H9, UniRef50_P06753
UniGene: Hs.535581, Hs.578978, Hs.644306, Hs.654421
CCDS: CCDS41403.1, CCDS41400.1, CCDS60275.1, CCDS1060.1, CCDS41402.1, CCDS60274.1, CCDS41401.1

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