| Type | Description |
|---|---|
| Definition | complement C2 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-19 13:43:00 | Complement protein levels and MBL2 polymorphisms are associated with dengue and disease severity. | 32913345 |
| 2020-11-28 13:11:00 | Hereditary Deficiency of the Second Component of Complement: Early Diagnosis and 21-Year Follow-Up of a Family. | 32164349 |
| 2019-07-06 11:16:00 | Logistic regression analyses showed that six C2 single nucleotide polymorphisms had significant associations with the risk of chronic hepatitis B and chronic hepatitis B-related hepatocellular carcinoma among the Korean subjects. Stepwise analysis revealed that causal markers (rs9267665 and rs10947223) were identified among the C2 variants. | 29283494 |
| 2019-01-05 11:22:00 | The pooled ORs for rs551397, rs2274700, rs4151667, rs641153, rs1047286, rs9332739, and rs547154 in the heterozygote model were 0.53, 0.53 , 0.54, 0.48, 1.42, 0.50, and 0.52, respectively. We confirmed the protective role of C2/CFB/CFH polymorphisms in the development of Age-Related Macular Degeneration (AMD), and showed single nucleotide polymorphism in C3 was a high-risk factor for AMD | 30179527 |
| 2017-12-16 12:11:00 | Vag8 binding to human C1-inhibitor (C1-inh) interferes with the binding of C1-inh to C1s, C1r and MASP-2, resulting in the release of active proteases that subsequently cleave C2 and C4 away from the bacterial surface. | 28742139 |
| Type | IDs |
|---|---|
| Synonymous | ARMD14, CO2 |
| Gene |
UniProtKB-ID:
CO2_HUMAN,
A0A0G2JL69_HUMAN,
B4DQI1_HUMAN,
Q5JP69_HUMAN,
Q8N6L6_HUMAN,
B4DV48_HUMAN,
Q53HP3_HUMAN
UniprotKB:
P06681,
A0A0G2JL69,
B4DQI1,
Q5JP69,
Q8N6L6,
B4DV48,
Q53HP3
UniParc:
UPI000007054A,
UPI000050A6C4,
UPI00017A78F4,
UPI00039189F9,
UPI00017A7DF3,
UPI000000DA4D,
UPI0001981E10,
UPI00017A7728
EMBL:
AK300930,
AK222537,
AL844853,
AL671762,
CR759782,
M15082,
KY500774,
L09707,
X04481,
L09708,
AK312581,
M15549,
CR388219,
KY500776,
AY349611,
CR933857,
AL662834,
CR759784,
AL662849,
BC043484,
AK300892,
BX005143,
M26301,
CH471081,
L09706,
BC029781,
AL645922,
AK298311,
AK298808,
AF019413,
KY500771
Ensembl:
ENSG00000206372,
ENSG00000204364,
ENSG00000166278,
ENSG00000235696,
ENSG00000235017,
ENSG00000226560,
ENSG00000231543
KO:
hsa:717
|
| Nucleutide sequences |
EMBL-CDS:
AAB67975.1,
AAB97607.1,
AAA35614.1,
BAG60565.1,
AAH43484.1,
AAQ15273.1,
AAA59624.1,
BAG62532.1,
CAA28169.1,
AAA59649.1,
BAG60943.1,
AQY77241.1,
EAX03549.1,
AQY77244.1,
AQY77246.1,
BAG35475.1,
AAH29781.1,
BAG62560.1,
BAD96257.1
Gene_ORFName:
hCG_43694
Ensembl_TRS:
ENST00000413548,
ENST00000618254,
ENST00000416252,
ENST00000612228,
ENST00000549972,
ENST00000548973,
ENST00000551648,
ENST00000383362,
ENST00000375510,
ENST00000442278,
ENST00000548995,
ENST00000448206,
ENST00000411803,
ENST00000615380,
ENST00000621558,
ENST00000551081,
ENST00000299367,
ENST00000452323,
ENST00000550682,
ENST00000550045,
ENST00000549997,
ENST00000552638,
ENST00000548828,
ENST00000550363,
ENST00000547984,
ENST00000614291,
ENST00000615801,
ENST00000548250,
ENST00000548500,
ENST00000469372,
ENST00000613837,
ENST00000618948,
ENST00000418949
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000446728,
ENSP00000449286,
ENSP00000299367,
ENSP00000449715,
ENSP00000450387,
ENSP00000407961,
ENSP00000480739,
ENSP00000447632,
ENSP00000446639,
ENSP00000372853,
ENSP00000402278,
ENSP00000395683,
ENSP00000405800,
ENSP00000392322,
ENSP00000482616,
ENSP00000392835,
ENSP00000483231,
ENSP00000364660,
ENSP00000481651,
ENSP00000449366,
ENSP00000449823,
ENSP00000450180,
ENSP00000449345,
ENSP00000447458,
ENSP00000448602,
ENSP00000482072,
ENSP00000482188,
ENSP00000483004,
ENSP00000449940,
ENSP00000478351,
ENSP00000418923,
ENSP00000447134,
ENSP00000406190
RefSeq:
NP_000054.2,
NP_001269387.1,
NP_001269388.1,
NP_001171534.1,
NP_001269386.1,
NP_001139375.1
|
| Others |
UniRef100:
UniRef100_Q53HP3,
UniRef100_B4DV48,
UniRef100_A0A0G2JL69,
UniRef100_B4DQI1,
UniRef100_Q8N6L6,
UniRef100_P06681
UniRef90:
UniRef90_Q8SQ75,
UniRef90_P06681,
UniRef90_P06681-3,
UniRef90_Q8N6L6
UniRef50:
UniRef50_Q8SQ75,
UniRef50_P06681,
UniRef50_P06681-3,
UniRef50_Q8N6L6
UniGene:
Hs.408903
CCDS:
CCDS54991.1,
CCDS4728.1,
CCDS56416.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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Ensembl: {{protein.nucleotideEnsembl}} |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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