| Type | Description |
|---|---|
| Definition | TNFRSF1A-associated via death domain |
| Date | Results | Publications |
|---|---|---|
| 2021-02-20 13:30:00 | Modulating TRADD to restore cellular homeostasis and inhibit apoptosis. | 32968279 |
| 2020-07-11 10:37:00 | deletion of Ripk3 is sufficient to rescue the neonatal lethality of Ripk1(-/-)Tradd(-/-) animals and delays but does not completely prevent early mortality. Although Ripk3 deletion provides a significant survival advantage, Ripk1(-/-)Tradd(-/-)Ripk3(-/-) animals die between 22 and 49 days, are runty compared to littermate controls and present with splenomegaly | 30185824 |
| 2020-05-09 12:12:00 | High TRADD expression promotes liver inflammatory response and liver carcinogenesis. | 31783009 |
| 2017-06-10 12:34:00 | TRADD knockout blunts pressure overload-induced cardiac hypertrophy through mediating TAK1/p38 MAPK but not AKT phosphorylation | 28013046 |
| 2014-04-05 12:36:00 | Data indicate that ASK1 activation stimulated the activity of the transcription factor FoxO3a, which increased the abundance of the apoptosis-promoting adaptor protein TRADD, leading to activation of caspase 8. | 23982205 |
| Type | IDs |
|---|---|
| Synonymous | 9130005N23Rik, AA930854 |
| Gene |
UniProtKB-ID:
TRADD_MOUSE,
B2RRZ7_MOUSE
UniprotKB:
Q3U0V2,
B2RRZ7
UniParc:
UPI00000238F8
EMBL:
BC138642,
BC132607,
AK156540
Ensembl:
ENSMUSG00000031887
KO:
mmu:71609
|
| Nucleutide sequences |
EMBL-CDS:
BAE33749.1,
AAI32608.1,
AAI38643.1
Ensembl_TRS:
ENSMUST00000034359
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000034359
RefSeq:
NP_001028333.1
|
| Others |
UniRef100:
UniRef100_Q3U0V2
UniRef90:
UniRef90_Q3U0V2
UniRef50:
UniRef50_Q15628
UniGene:
Mm.264255
CCDS:
CCDS22594.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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