Type | Description |
---|---|
Definition | DNA topoisomerase I |
Date | Results | Publications |
---|---|---|
2021-04-13 10:14:00 | [The Efficacy of topo -pS10 Expression in Gastric Cancer as a Predictive Biomarker for Irinotecan Use]. | 33790151 |
2021-03-20 13:35:00 | Proteome dynamics at broken replication forks reveal a distinct ATM-directed repair response suppressing DNA double-strand break ubiquitination. | 33450211 |
2020-09-26 13:09:00 | Topoisomerase 1 prevents replication stress at R-loop-enriched transcription termination sites. | 32769985 |
2020-09-12 16:04:00 | Dual Processing of R-Loops and Topoisomerase I Induces Transcription-Dependent DNA Double-Strand Breaks. | 31533039 |
2020-08-29 12:48:00 | Topoisomerase I-driven repair of UV-induced damage in NER-deficient cells. | 32513688 |
Type | IDs |
---|---|
Synonymous | TOPI |
Gene |
UniProtKB-ID:
TOP1_HUMAN,
Q9BVT2_HUMAN
UniprotKB:
P11387,
Q9BVT2
UniParc:
UPI000004F0B1,
UPI00000706C5
EMBL:
M60695,
M60692,
M60688,
M60704,
AL035652,
M60701,
M60698,
M60689,
M60702,
M60697,
M60694,
X16479,
M60706,
M60700,
M60691,
M60690,
CH471077,
U07804,
U07806,
AK292943,
X52601,
M27913,
M60696,
M60703,
M60699,
M60693,
M60705,
AL022394,
J03250,
BC000943
Ensembl:
ENSG00000198900
KO:
hsa:7150
|
Nucleutide sequences |
EMBL-CDS:
AAA61208.1,
EAW75994.1,
AAA61207.1,
CAA36834.1,
AAB60379.1,
BAF85632.1,
AAB60380.1,
CAA34500.2,
AAA61206.1,
EAW75995.1,
AAH00943.1
Ensembl_TRS:
ENST00000361337
|
Protein sequencees |
Ensembl_PRO:
ENSP00000354522
RefSeq:
NP_003277.1
|
Others |
UniRef100:
UniRef100_H2P1X8,
UniRef100_P11387
UniRef90:
UniRef90_F1PUE0,
UniRef90_P11387
UniRef50:
UniRef50_P11387
UniGene:
Hs.472737
CCDS:
CCDS13312.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
排名 | 科研单位 | 文献 |
---|---|---|
{{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
排名 | 研究人员 | 文献 |
---|---|---|
{{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员