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71461 Ptk7

71461

Ptk7

PTK7 protein tyrosine kinase 7

protein-coding

Mus musculus

基因描述

Type Description
Definition PTK7 protein tyrosine kinase 7

研究结论

Date Results Publications
2018-06-02 12:06:00 PTK7 regulates extracellular matrix integrity and the activity levels of RAC1 and myosin II, which in turn regulates Wolffian duct morphogenesis and therefore, epididymal function. 29580943
2017-07-01 11:57:00 In a Ptk7-deficient mouse strain, loss of Ptk7 leads to a diminished pool of hematopoietic stem cells but does not affect in vitro or in vivo differentiation. This is correlated with increased quiescence and reduced homing abilities of Ptk7-deficient hematopoietic stem and progenitor cells. 27183644
2016-09-10 11:22:00 Data suggest that protein tyrosine kinase 7 (PTK7) is essential for Wolffian duct morphogenesis and male fertility. 26944093
2015-12-05 10:13:00 data demonstrates that PTK7 regulates the activity of KDR biphasically by inducing oligomerization of KDR molecules at lower concentrations and by surrounding KDR molecules at higher concentrations. 25986862
2014-11-08 11:54:00 PTK7 expression plays an important role in the invasiveness of intrahepatic cholangiocarcinoma cells. 24587299

名称对应

Type IDs
Synonymous 8430404F20Rik, chz, mPTK7/CCK4
Gene
UniProtKB-ID: PTK7_MOUSE
UniprotKB: Q8BKG3
UniParc: UPI00000EB59D
EMBL: AK053044, AB055408, BC076578, AK163135, BC027800, AF531873, AK018379, AY303976
Ensembl: ENSMUSG00000023972
KO: mmu:71461
Nucleutide sequences
EMBL-CDS: BAC53806.1, BAE43251.1, BAC35248.1, BAE37208.1, AAH27800.1, AAH76578.1, AAQ10071.1, AAQ73496.1
Ensembl_TRS: ENSMUST00000044442
Protein sequencees
Ensembl_PRO: ENSMUSP00000043703
RefSeq: XP_017173127.1, XP_006524987.1, XP_006524985.2, XP_006524986.1, NP_780377.1
Others
UniRef100: UniRef100_Q8BKG3
UniRef90: UniRef90_Q13308
UniRef50: UniRef50_Q13308
UniGene: Mm.181833
CCDS: CCDS37637.1

全选

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