| Type | Description |
|---|---|
| Definition | troponin T3, fast skeletal type |
| Date | Results | Publications |
|---|---|---|
| 2019-05-04 11:36:00 | The TnT3 appears to contribute to age-related sarcopenia and possibly other age-related deficiencies such as muscle insulin resistance and beta cell dysfunction by interacting with TnT3-binding sequences in the promoter area of p53-related genes, among others, and consequently modulating the transcriptional regulation of these target genes. | 29596868 |
| 2016-08-06 11:12:00 | Three homologous genes have evolved in vertebrates to encode three muscle type-specific TnT isoforms: TNNT1 for slow skeletal muscle TnT, TNNT2 for cardiac muscle TnT, and TNNT3 for fast skeletal muscle TnT. | 26774798 |
| 2016-07-16 11:29:00 | The presence of the p.(Arg63His) missense mutation at position 63 of TNNT3 was confirmed through direct cycle sequencing of genomic DNA in six affected South African family members for whom DNA had been archived. | 26915936 |
| 2011-10-01 10:56:00 | Data show that a missense mutation at nucleotide position 187 in exon 9 of the TNNT3 gene was identified in all affected individuals in the family. | 21402185 |
| 2010-09-15 22:06:00 | Observational study of gene-disease association. (HuGE Navigator) | 20634891 |
| Type | IDs |
|---|---|
| Synonymous | TNTF, beta-TnTF |
| Gene |
UniProtKB-ID:
TNNT3_HUMAN,
H9KVA2_HUMAN
UniprotKB:
P45378,
H9KVA2
UniParc:
UPI000066D8D2,
UPI00003B5D08,
UPI0000141B37,
UPI0000049C92,
UPI000198C548,
UPI0000ED9058,
UPI0000049C94,
UPI000013DB6C
EMBL:
BX640689,
KF455299,
CR541927,
AF026276,
BC117327,
BT019997,
BC171727,
AK056968,
U14641,
DQ778624,
M21984,
U14643,
BC050446,
AC051649,
U14642,
U14644,
BC143537
Ensembl:
ENSG00000288250,
ENSG00000130595
KO:
hsa:7140
|
| Nucleutide sequences |
EMBL-CDS:
AAH50446.1,
AAI43538.1,
AAI71727.1,
AAA50360.1,
AAA50359.1,
AAF21629.1,
CAG46725.1,
CAE45814.1,
AAA36777.1,
AAV38800.1,
ABG77458.1,
AAA50361.1,
AAA50362.1,
BAG51835.1,
AAI17328.1
Ensembl_TRS:
ENST00000381589,
ENST00000673503,
ENST00000673572,
ENST00000381579,
ENST00000381563,
ENST00000641119,
ENST00000397301,
ENST00000381558,
ENST00000673174,
ENST00000278317,
ENST00000672214,
ENST00000673082,
ENST00000671850,
ENST00000641787,
ENST00000672629,
ENST00000673157,
ENST00000344578,
ENST00000672659,
ENST00000397304
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000500846,
ENSP00000344870,
ENSP00000500606,
ENSP00000500796,
ENSP00000499917,
ENSP00000278317,
ENSP00000380468,
ENSP00000493331,
ENSP00000500705,
ENSP00000371001,
ENSP00000500263,
ENSP00000370975,
ENSP00000492914,
ENSP00000370970,
ENSP00000500437,
ENSP00000500081,
ENSP00000500156,
ENSP00000370991,
ENSP00000380471
RefSeq:
XP_016873703.1,
NP_001036245.1,
XP_016873706.1,
NP_001354772.1,
NP_001036246.1,
NP_001350490.1,
XP_016873698.1,
NP_006748.1,
XP_006718363.1,
NP_001354773.1,
XP_006718357.1,
XP_024304438.1,
XP_016873702.1,
NP_001284575.1,
NP_001354771.1,
XP_016873705.1,
XP_016873699.1,
NP_001354780.1,
XP_016873697.1,
XP_006718351.1,
XP_006718362.1,
NP_001354774.1,
XP_011518645.1,
XP_016873701.1,
XP_024304440.1,
XP_016873700.1,
XP_016873704.1,
XP_016873707.1,
XP_016873694.1,
XP_016873696.1,
NP_001354777.1,
XP_016873708.1,
NP_001036247.1,
XP_016873695.1,
XP_024304439.1,
NP_001354778.1,
NP_001354776.1,
NP_001354775.1,
NP_001354781.1,
NP_001354779.1,
XP_024304437.1
|
| Others |
UniRef100:
UniRef100_H9KVA2,
UniRef100_P45378
UniRef90:
UniRef90_P45378-7,
UniRef90_P45378
UniRef50:
UniRef50_P13805,
UniRef50_P45378
UniGene:
Hs.73454
CCDS:
CCDS41596.1,
CCDS41594.1,
CCDS86164.1,
CCDS41595.1,
CCDS7727.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员