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7138 TNNT1

7138

TNNT1

troponin T1, slow skeletal type

protein-coding

Homo sapiens

基因描述

Type Description
Definition troponin T1, slow skeletal type

研究结论

Date Results Publications
2021-02-13 13:23:00 Troponin T but not C reactive protein is associated with future surgery for aortic stenosis: a population-based nested case-referent study. 33051334
2020-08-01 15:05:00 Three adults and 1 child shared a novel missense homozygous variant in the TNNT1 gene (NM_003283.6: c.287T > C; p.Leu96Pro). This study expands the phenotypic spectrum of TNNT1 myopathy. 31970803
2020-01-18 12:38:00 These findings indicated that TNNT1 may promote the progression of colon adenocarcinoma, mediating epithelial-mesenchymal transition process, and thus shed a novel light on colon adenocarcinoma therapeutic treatments. 31512553
2019-08-17 10:14:00 In a nationwide cohort in Sweden, patients with a first myocardial infarction had increased levels of Troponin T. 29880121
2019-03-16 10:16:00 Similar functional and histological phenotypes were observed in other human cohorts and two transgenic murine models (Tnnt1-/- and Tnnt1 c.505G>T). These findings have implications for emerging molecular therapies, including the suitably of TNNT1 gene replacement for newborns with 'Amish' nemaline myopathy or other TNNT1-associated myopathies. 29931346

名称对应

Type IDs
Synonymous ANM, NEM5, STNT, TNT, TNTS
Gene
UniProtKB-ID: TNNT1_HUMAN
UniprotKB: P13805
UniParc: UPI000016A37B, UPI0000000CAF, UPI0000072B0F
EMBL: S66057, AJ011713, BC010963, S66170, BC034143, S69209, AJ011712, M19309, BC022086, M19308, BT019630, S69208
Ensembl: ENSG00000105048
KO: hsa:7138
Nucleutide sequences
EMBL-CDS: AAH22086.2, AAH34143.1, AAD13978.1, CAA09751.1, AAB30272.1, CAA09750.1, AAB30273.1, AAH10963.1, CAA09752.1, AAV38436.1, AAA61204.1, AAA61205.1
Ensembl_TRS: ENST00000356783, ENST00000588981, ENST00000291901, ENST00000587758
Protein sequencees
Ensembl_PRO: ENSP00000467789, ENSP00000349233, ENSP00000467176, ENSP00000291901
RefSeq: XP_016882675.1, XP_011525548.1, XP_016882676.1, NP_003274.3, NP_001119604.1, NP_001278703.1, NP_001119605.1
Others
UniRef100: UniRef100_P13805
UniRef90: UniRef90_P13805
UniRef50: UniRef50_P13805
UniGene: Hs.631558
CCDS: CCDS46185.1, CCDS12917.1, CCDS59421.1

全选

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