| Type | Description |
|---|---|
| Definition | apoptosis-inducing factor, mitochondrion-associated 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-02-16 11:20:00 | the brain-specific isoform of AIF, AIF-2, constitutively expressed in mouse hippocampal HT22 cell lines, where it exerts protective effects against oxygen and glucose deprivation-induced mitochondrial dysfunction, oxidative stress and apoptosis through inhibiting the nuclear translocation of AIF-1. | 28732772 |
| 2016-12-17 10:39:00 | 4-hydroxy-2-nonenal adduction of AIFm2 shifts the function of AIFm2 from an NADH oxidoreductase to a proapototic protein. | 26689472 |
| 2015-10-03 10:55:00 | Aifm2 may function in differentiation of erythroid murine erythroleukemia line cells in vitro. | 26168492 |
| 2011-08-06 10:37:00 | Results demonstrate nuclear AIF translocation only in PARG-null TS cells, which demonstrates the presence of AIF-mediated cell death. | 21366272 |
| 2010-01-21 00:00:00 | AMID is not required for normal development and p53-mediated tumor suppression. | 16186796 |
| Type | IDs |
|---|---|
| Synonymous | 5430437E11Rik, Amid, D730001I10Rik, PRG3 |
| Gene |
UniProtKB-ID:
FSP1_MOUSE
UniprotKB:
Q8BUE4
UniParc:
UPI000002180B,
UPI00005651FE
EMBL:
BC038129,
AC153136,
AK155240,
AK147741,
AK085656
Ensembl:
ENSMUSG00000020085
KO:
mmu:71361
|
| Nucleutide sequences |
EMBL-CDS:
BAE33142.1,
AAH38129.1,
BAE28108.1,
BAC39497.1
Ensembl_TRS:
ENSMUST00000105455,
ENSMUST00000080099,
ENSMUST00000099706,
ENSMUST00000067857
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000101095,
ENSMUSP00000097297,
ENSMUSP00000070054,
ENSMUSP00000078998
RefSeq:
XP_011241875.1,
XP_036011907.1,
XP_011241874.1,
NP_722474.2,
NP_835159.1,
XP_006514187.1,
XP_006514185.1,
XP_006514188.1,
XP_006514189.1,
NP_001271229.1,
XP_006514184.1,
NP_001034283.1,
XP_006514190.1
|
| Others |
UniRef100:
UniRef100_Q8BUE4
UniRef90:
UniRef90_Q9BRQ8
UniRef50:
UniRef50_Q9BRQ8
UniGene:
Mm.286309
CCDS:
CCDS48576.1,
CCDS23884.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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