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71279 Slc29a3

71279

Slc29a3

solute carrier family 29 (nucleoside transporters), member 3

protein-coding

Mus musculus

基因描述

Type Description
Definition solute carrier family 29 (nucleoside transporters), member 3

研究结论

Date Results Publications
2019-12-07 10:29:00 These results identify ENT3 as a vital metabolite transporter that supports T cell homeostasis and activation by regulating lysosomal integrity and the availability of nucleosides. 29791845
2019-09-14 11:54:00 adult stem cell deficits that drive ENT3-related abnormalities in mice, were identified. 31270333
2012-01-28 12:16:00 study found mice lacking ENT3 developed spontaneous and progressive macrophage-dominated histiocytosis; in absence of ENT3, defective apoptotic cell clearance led to lysosomal nucleoside buildup, elevated intralysosomal pH and altered macrophage function 22174130
2010-05-10 12:01:00 Mutation analysis of candidate genes within the target interval identified biallelic germline mutations in SLC29A3 in the Faisalabad histiocytosis kindred and in two families reported to have familial Rosai-Dorfman disease. 20140240
2010-01-21 00:00:00 broad selectivity, low affinity nucleoside transporter that can also transport adenine 15701636

名称对应

Type IDs
Synonymous 4933435C21Rik, AW987637, Ent3
Gene
UniProtKB-ID: S29A3_MOUSE
UniprotKB: Q99P65
UniParc: UPI00000284D0
EMBL: CH466553, AF326986, BC137864, AK034133
Ensembl: ENSMUSG00000020100
KO: mmu:71279
Nucleutide sequences
EMBL-CDS: AAI37865.1, AAK00957.1, EDL32166.1, BAC28600.1
Ensembl_TRS: ENSMUST00000117513
Protein sequencees
Ensembl_PRO: ENSMUSP00000112685
RefSeq: XP_006514182.1, XP_006514183.1, XP_006514181.1, NP_076085.1
Others
UniRef100: UniRef100_Q99P65
UniRef90: UniRef90_Q80WK7
UniRef50: UniRef50_Q9BZD2
UniGene: Mm.284462
CCDS: CCDS48571.1

全选

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研究热度

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