| Type | Description |
|---|---|
| Definition | regulatory factor X, 4 (influences HLA class II expression) |
| Date | Results | Publications |
|---|---|---|
| 2018-02-17 11:51:00 | provide a novel conditional KO animal model in which to investigate the downstream genes directly and/or indirectly regulated by RFX4 isoform 1. This model could provide new insights into the pathogenesis of obstructive hydrocephalus and holoprosencephaly in humans, both relatively common and disabling birth defects | 29298325 |
| 2010-02-15 11:25:00 | the dominant Rfx4 transcript present begins at a downstream exon and lacks the DNA binding domain | 19596083 |
| 2010-01-21 00:00:00 | Rfx4 is a regionally specific transcriptional regulator of ciliogenesis and thus is also a regionally specific modulator of Shh signaling during development of the central nervous system. | 19887680 |
| 2010-01-21 00:00:00 | mouse regulatory factor X4 transcript is expressed in the suprachiasmatic nucleus and regulated by light | 14701801 |
| 2010-01-21 00:00:00 | Data implicate the RFX4_v3 variant transcript as being crucial for early brain development, as well as for the genesis of the subcommissural organ. | 12925582 |
| Type | IDs |
|---|---|
| Synonymous | 4933412G19Rik, NYD-sp10 |
| Gene |
UniProtKB-ID:
RFX4_MOUSE
UniprotKB:
Q7TNK1
UniParc:
UPI00001B62B6,
UPI00000217E6,
UPI0000214137,
UPI00016277E6
EMBL:
AY342003,
BC138720,
BC138719,
AB089184,
AK016791,
AB086957,
AK034131,
AY102010,
AK132673
Ensembl:
ENSMUSG00000020037
KO:
mmu:71137
|
| Nucleutide sequences |
EMBL-CDS:
BAE21294.1,
BAD07409.1,
BAC28598.1,
BAB30432.1,
AAI38720.1,
AAQ17042.1,
BAD07408.1,
AAI38721.1,
AAM52485.2
Ensembl_TRS:
ENSMUST00000060397,
ENSMUST00000095388,
ENSMUST00000166696
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000093035,
ENSMUSP00000128690,
ENSMUSP00000051107
RefSeq:
XP_006514178.1,
NP_001020089.1,
XP_006514176.1,
NP_081965.2,
XP_030101139.1,
XP_006514177.1,
XP_030101138.1
|
| Others |
UniRef100:
UniRef100_Q7TNK1
UniRef90:
UniRef90_Q7TNK1
UniRef50:
UniRef50_Q7TNK1
UniGene:
Mm.79070
CCDS:
CCDS24083.1,
CCDS24082.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员