| Type | Description |
|---|---|
| Definition | SEC62 homolog, preprotein translocation factor |
| Date | Results | Publications |
|---|---|---|
| 2020-06-20 12:33:00 | miR-4429 prevented gastric cancer progression through targeting METTL3 to inhibit m(6)A-caused stabilization of SEC62 | 31395342 |
| 2020-06-06 10:04:00 | In tissue samples from 53 breast cancer patients,found increased SEC62 protein levels in tumor tissue compared to tumor-free tissue from the same patients. Tumors with high SEC62 expression or containing isolated cells with high SEC62 staining had more frequently distant metastases. ). Overall survival was significantly worse in BC patients with high SEC62 expression and in cases with isolated-intense SEC62 staining. | 30747329 |
| 2018-02-24 10:59:00 | Results show higher SEC62 in the lymph node metastases from head and neck squamous cell carcinomas and cervical cancer of unknown primary patients compared with the primary tumor. Tumors from N1 to N3 stage exhibit increasing SEC62 expression in the lymphatic metastases. Its knockdown resulted in tumor cell line migration inhibition while, its overexpression stimulated cell migration. | 28002801 |
| 2017-09-30 11:14:00 | High Sec62 expression is associated with dysplastic cervical lesions. | 27553742 |
| 2017-05-27 10:13:00 | identify Sec62 as a critical molecular component in maintenance and recovery of endoplasmic reticulum homeostasis | 27749824 |
| Type | IDs |
|---|---|
| Synonymous | Dtrp1, HTP1, TLOC1, TP-1 |
| Gene |
UniProtKB-ID:
SEC62_HUMAN,
D3DNQ1_HUMAN
UniprotKB:
Q99442,
D3DNQ1
UniParc:
UPI000007186C,
UPI0000E20073
EMBL:
AB024586,
CH471052,
BC012035,
U93239,
D87127
Ensembl:
ENSG00000008952
KO:
hsa:7095
|
| Nucleutide sequences |
EMBL-CDS:
EAW78530.1,
AAB51391.1,
EAW78531.1,
BAB12685.1,
BAA13254.1,
AAH12035.1,
EAW78528.1,
EAW78529.1
Gene_ORFName:
hCG_16182
Ensembl_TRS:
ENST00000337002,
ENST00000480708
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000420331,
ENSP00000337688
RefSeq:
XP_011511416.1,
NP_003253.1
|
| Others |
UniRef100:
UniRef100_Q99442,
UniRef100_D3DNQ1
UniRef90:
UniRef90_Q99442
UniRef50:
UniRef50_Q99442
UniGene:
Hs.744859
CCDS:
CCDS3210.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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