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7091 TLE4

7091

TLE4

TLE family member 4, transcriptional corepressor

protein-coding

Homo sapiens

基因描述

Type Description
Definition TLE family member 4, transcriptional corepressor

研究结论

Date Results Publications
2018-06-30 11:20:00 Genes TGFB1, TLE4 and MUC22 are associated with the risk of childhood asthma in Chinese population. 28262390
2017-07-29 11:57:00 the loss of TLE4 confers proliferative advantage to leukemic cells, simultaneous with an upregulation of a pro- inflammatory signature mediated through aberrant increases in Wnt signaling activity 27486062
2016-11-12 10:03:00 the results suggested that TLE4, a potential prognostic biomarker for colorectal cancer, plays an important role in the development and progression of human colorectal cancer. 26701208
2015-05-30 12:14:00 PPM1B interacts with Groucho 4 and is localized to DNA in a Groucho-dependent manner, and phosphatase activity is required for transcriptional silencing. 25631048
2014-05-03 10:33:00 Groucho related gene Grg4 robustly activates the expression of a BMP reporter gene, as well as enhancing and sustaining the upregulation of the endogenous Id1 gene induced by BMP7. 24099773

名称对应

Type IDs
Synonymous BCE-1, BCE1, E(spI), E(spl), ESG, ESG4, GRG4, Grg-4
Gene
UniProtKB-ID: TLE4_HUMAN
UniprotKB: Q04727
UniParc: UPI000056D4A8, UPI00005AB2D8, UPI00017A7176, UPI00001CE3BA
EMBL: AB033087, AL353813, AL358975, BC045650, BC059405, AK296342, M99439, AL162059, AL445252
Ensembl: ENSG00000106829
KO: hsa:7091
Nucleutide sequences
EMBL-CDS: AAH59405.2, BAG59027.1, CAB82397.1, BAA86575.1, AAA61195.1, AAH45650.1
Ensembl_TRS: ENST00000265284, ENST00000376537, ENST00000376552, ENST00000376544
Protein sequencees
Ensembl_PRO: ENSP00000365735, ENSP00000265284, ENSP00000365720, ENSP00000365727
RefSeq: XP_011517272.1, XP_016870556.1, NP_001269682.1, XP_011517259.1, NP_001338493.1, XP_011517260.1, NP_001338475.1, XP_006717327.1, XP_011517264.1, XP_011517257.1, XP_016870563.1, XP_011517270.1, XP_011517258.1, XP_016870557.1, NP_001269689.1, NP_001338481.1, XP_016870572.1, XP_011517263.1, XP_016870570.1, NP_001269678.1, NP_001269677.1, NP_008936.2, NP_001338471.1, XP_011517268.1, NP_001338492.1, XP_011517265.1, XP_011517255.1, NP_001338489.1, XP_011517267.1, NP_001338487.1, XP_011517271.1, NP_001338476.1, XP_016870564.1, XP_006717331.1, NP_001338491.1, XP_011517254.1, XP_011517261.1, XP_016870559.1, XP_011517269.1, XP_016870558.1, XP_011517274.1, NP_001338485.1, XP_024303427.1, XP_011517256.1, NP_001338470.1, XP_011517266.1, NP_001338479.1, NP_001338472.1, XP_011517262.1
Others
UniRef100: UniRef100_Q04727
UniRef90: UniRef90_Q04727
UniRef50: UniRef50_Q04724
UniGene: Hs.444213
CCDS: CCDS65070.1, CCDS75851.1, CCDS65069.1, CCDS43837.1

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