| Type | Description |
|---|---|
| Definition | tubulin tyrosine ligase-like family, member 7 |
| Date | Results | Publications |
|---|---|---|
| 2015-08-01 11:47:00 | TTLL7, the most abundant neuronal glutamylase, adds glutamates preferentially to the beta-tubulin tail; coupled with ensemble and single-molecule biochemistry, the hybrid X-ray and cryo-electron microscopy structure of TTLL7 bound to the microtubule delineates a tripartite microtubule recognition strategy. | 25959773 |
| 2010-01-21 00:00:00 | TTLL7 is a mammalian beta-tubulin polyglutamylase required for growth of MAP2-positive neurites | 16901895 |
| 2010-01-21 00:00:00 | TTLL7 performs both the initiation and elongation of polyglutamylation on beta-tubulin; the mechanism of binding of three substrates glutamate, ATP, and tubulin to the enzyme is a random sequential pathway. | 19152315 |
| Type | IDs |
|---|---|
| Synonymous | 1110049N09Rik, 4921517B04Rik, C630030B20, mTTLL7 |
| Gene |
UniProtKB-ID:
TTLL7_MOUSE,
A0A0G2LB90_MOUSE
UniprotKB:
A4Q9F0,
A0A0G2LB90
UniParc:
UPI00000245B8,
UPI0001F78E45,
UPI00014F733E
EMBL:
AK083236,
AC165225,
AM690750,
AM690751,
AC115889,
AK014905
Ensembl:
ENSMUSG00000036745
KO:
mmu:70892
|
| Nucleutide sequences |
EMBL-CDS:
BAC38821.1,
BAB29613.1,
CAM84328.1,
CAM84327.1
Ensembl_TRS:
ENSMUST00000037942
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000043753
RefSeq:
NP_001289886.1,
XP_036019208.1,
NP_001344146.1,
NP_001289887.1,
XP_036019205.1,
XP_036019206.1,
XP_036019207.1
|
| Others |
UniRef100:
UniRef100_A4Q9F0,
UniRef100_A0A0G2LB90
UniRef90:
UniRef90_A4Q9F0
UniRef50:
UniRef50_Q6ZT98
UniGene:
Mm.187793
CCDS:
CCDS51094.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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