| Type | Description |
|---|---|
| Definition | PWWP domain containing 2A |
| Date | Results | Publications |
|---|---|---|
| 2019-01-19 10:07:00 | Study in HeLa, HEK293F, and mouse embryonic stem cells reveal that loss of PWWP2A/B leads to increases in histone acetylation predominantly at highly expressed genes, accompanied by decreases in Pol II elongation. Collectively, these findings suggest a role for PWWP2A/B in regulating transcription through the fine-tuning of histone acetylation dynamics at actively transcribed genes. | 30228260 |
| Type | IDs |
|---|---|
| Synonymous | 4631424J17Rik, AI891583, AU024105, D930040F23Rik |
| Gene |
UniProtKB-ID:
PWP2A_MOUSE
UniprotKB:
Q69Z61
UniParc:
UPI000047188C,
UPI000059DC4A
EMBL:
AL732633,
AK173305,
AK171257,
AK014534
Ensembl:
ENSMUSG00000044950
KO:
mmu:70802
|
| Nucleutide sequences |
EMBL-CDS:
CAM20715.1,
BAD32583.1,
BAE42348.1,
CAM20714.1,
BAB29417.1
Ensembl_TRS:
ENSMUST00000094294,
ENSMUST00000061070
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000054154,
ENSMUSP00000091852
RefSeq:
XP_011247561.1,
XP_011247559.1,
XP_006534271.1,
NP_001157703.1,
NP_081833.1,
XP_006534263.1,
XP_030102170.1,
NP_001350070.1,
XP_036012879.1,
NP_001350071.1,
XP_036012880.1
|
| Others |
UniRef100:
UniRef100_Q69Z61
UniRef90:
UniRef90_Q69Z61
UniRef50:
UniRef50_Q96N64-2
UniGene:
Mm.397449,
Mm.475270
CCDS:
CCDS48774.1,
CCDS48773.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 30228260 |
Nat Commun Tianyi Zhang , Guifeng Wei , Christopher J Millard , Roman Fischer , Rebecca Konietzny , Benedikt M Kessler , John W R Schwabe , Neil Brockdorff |
2018-09-18 | - |
| 21267068 |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. Graciana Diez-Roux , Sandro Banfi , Marc Sultan , Lars Geffers , Santosh Anand , David Rozado , Alon Magen , Elena Canidio , Massimiliano Pagani , Ivana Peluso , Nathalie Lin-Marq , Muriel Koch , Marchesa Bilio , Immacolata Cantiello , Roberta Verde , Cristian De Masi , Salvatore A Bianchi , Juliette Cicchini , Elodie Perroud , Shprese Mehmeti , Emilie Dagand , Sabine Schrinner , Asja Nürnberger , Katja Schmidt , Katja Metz , Christina Zwingmann , Norbert Brieske , Cindy Springer , Ana Martinez Hernandez , Sarah Herzog , Frauke Grabbe , Cornelia Sieverding , Barbara Fischer , Kathrin Schrader , Maren Brockmeyer , Sarah Dettmer , Christin Helbig , Violaine Alunni , Marie-Annick Battaini , Carole Mura , Charlotte N Henrichsen , Raquel Garcia-Lopez , Diego Echevarria , Eduardo Puelles , Elena Garcia-Calero , Stefan Kruse , Markus Uhr , Christine Kauck , Guangjie Feng , Nestor Milyaev , Chuang Kee Ong , Lalit Kumar , MeiSze Lam , Colin A Semple , Attila Gyenesei , Stefan Mundlos , Uwe Radelof , Hans Lehrach , Paolo Sarmientos , Alexandre Reymond , Duncan R Davidson , Pascal Dollé , Stylianos E Antonarakis , Marie-Laure Yaspo , Salvador Martinez , Richard A Baldock , Gregor Eichele , Andrea Ballabio |
2011-01-18 | - |
| 18799693 |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. Gwenn M Hansen , Diane C Markesich , Michael B Burnett , Qichao Zhu , Karen M Dionne , Lizabeth J Richter , Richard H Finnell , Arthur T Sands , Brian P Zambrowicz , Alejandro Abuin |
2008-10-01 |
Gm11335,
Gm17762,
A930017K11Rik,
BC028777,
Gm13999,
Gm11696,
Gm12359,
Gm10589,
D030047H15Rik,
Gm10856,
Gm10685,
Gm10062,
Gm10433,
Gm10648,
Gm10840,
Gm15441,
Gm10684,
Gm9900,
Gm10822,
Gm10687,
Gm11744,
Gm10747,
Arih2os,
B230344G16Rik,
Fmr1os,
Tmem51os1,
Gm14488,
Gm13033,
Gm10789,
Gm10615,
Gm1976,
Gm9967,
Gm9917,
Gm1974,
Gm11496,
Gm13580,
Gm2085,
Gm2183,
Gm2245,
Tbx3os1,
Gm12980,
Gm2329,
Lncenc1,
Gm2381,
Snhg12,
Gm2479,
Gm12942,
Gm2529,
Gm2533,
Rpl30-ps7,
Rsf1os2,
Gm2695,
2810416G20Rik,
Rpl30-ps6,
Gm2773,
Gm2788,
Dynlt1f,
Gm9793,
Gm2885,
Gm2920,
Gm15506,
Gm11627,
Gm10518,
Gm13496,
Gm3134,
Gm12827,
Gm3143,
Gm10144,
Ahnak2,
Gm3196,
Gm13242,
Gm3325,
Gm13247,
Gm10863,
Gm13157,
4930522L14Rik,
Gm3552,
Gm15226,
Gm3604,
Gm3643,
BC005561,
Gm3716,
2810410L24Rik,
Gm10282,
Gm3839,
Nhsl2,
4732419C18Rik,
Gm3906,
Gm3973,
Gm4013,
Apol7d,
Gm12057,
Gm10489,
Rex2,
1110002L01Rik,
Gm4189,
Gm4204,
4632428C04Rik,
9130023H24Rik
|
| 16141073 |
Antisense transcription in the mammalian transcriptome. Science S Katayama , Y Tomaru , T Kasukawa , K Waki , M Nakanishi , M Nakamura , H Nishida , C C Yap , M Suzuki , J Kawai , H Suzuki , P Carninci , Y Hayashizaki , C Wells , M Frith , T Ravasi , K C Pang , J Hallinan , J Mattick , D A Hume , L Lipovich , S Batalov , P G Engström , Y Mizuno , M A Faghihi , A Sandelin , A M Chalk , S Mottagui-Tabar , Z Liang , B Lenhard , C Wahlestedt , RIKEN Genome Exploration Research Group , Genome Science Group (Genome Network Project Core Group) , FANTOM Consortium |
2005-09-02 |
Gm14018,
Gm14964,
F630206G17Rik,
Oog3,
Notumos,
Ldlrap1,
Mdn1,
Pydc3,
9330171B17Rik,
Mfap1b,
Tmsb15b2,
Gm12802,
E430020m11rik,
Gm11335,
Gm15772,
Gm17762,
A930017K11Rik,
LOC100036513,
Gata5os,
Umad1,
Gm16982,
Gm9887,
Gm9872,
LOC100036530,
Gm9934,
Gm9913,
Gm11149,
BC028777,
Gm13999,
LOC100036540,
Gm9744,
Gm9983,
D630002J18Rik,
Gm16525,
Gm11696,
Dnajc3,
9430060I03Rik,
Gm12359,
4921516A02Rik,
Fam129c,
Gm10589,
Rsph3b,
Rnaset2a,
5430403G19Rik,
D030047H15Rik,
Gm13274,
B930046K06Rik,
Gm10862,
Gm10792,
Gm10802,
Gm10532,
G730003C15Rik,
Runx2os1,
Gm15612,
Gm10856,
Gm10857,
Gm10685,
Gm10803,
Gm10723,
F630028O10Rik,
Gm10836,
Gm10405,
Gm10513,
Gm10609,
F630201L12Rik,
4932427H20Rik,
Zfp389,
Gm10763,
Gm10062,
Gm10714,
Gm10531,
Gm10876,
Gm10750,
Gm10433,
Gm10837,
Gm10647,
Gm10648,
Gm10650,
Gm10610,
F830115B05Rik,
Gm10473,
Gm10614,
Gm10286,
G730046D07Rik,
Gm10287,
Gm10785,
Gm10183,
Gm10512,
1700061E17Rik,
Gm44113,
Gm10579,
Gm10741,
Gm10827,
Gm10522,
Gm10536,
Gm15998,
Faddos,
D130050E23Rik,
Gm10735
|
| 16141072 |
The transcriptional landscape of the mammalian genome. Science P Carninci , T Kasukawa , S Katayama , J Gough , M C Frith , N Maeda , R Oyama , T Ravasi , B Lenhard , C Wells , R Kodzius , K Shimokawa , V B Bajic , S E Brenner , S Batalov , A R R Forrest , M Zavolan , M J Davis , L G Wilming , V Aidinis , J E Allen , A Ambesi-Impiombato , R Apweiler , R N Aturaliya , T L Bailey , M Bansal , L Baxter , K W Beisel , T Bersano , H Bono , A M Chalk , K P Chiu , V Choudhary , A Christoffels , D R Clutterbuck , M L Crowe , E Dalla , B P Dalrymple , B de Bono , G Della Gatta , D di Bernardo , T Down , P Engstrom , M Fagiolini , G Faulkner , C F Fletcher , T Fukushima , M Furuno , S Futaki , M Gariboldi , P Georgii-Hemming , T R Gingeras , T Gojobori , R E Green , S Gustincich , M Harbers , Y Hayashi , T K Hensch , N Hirokawa , D Hill , L Huminiecki , M Iacono , K Ikeo , A Iwama , T Ishikawa , M Jakt , A Kanapin , M Katoh , Y Kawasawa , J Kelso , H Kitamura , H Kitano , G Kollias , S P T Krishnan , A Kruger , S K Kummerfeld , I V Kurochkin , L F Lareau , D Lazarevic , L Lipovich , J Liu , S Liuni , S McWilliam , M Madan Babu , M Madera , L Marchionni , H Matsuda , S Matsuzawa , H Miki , F Mignone , S Miyake , K Morris , S Mottagui-Tabar , N Mulder , N Nakano , H Nakauchi , P Ng , R Nilsson , S Nishiguchi , S Nishikawa , F Nori , O Ohara , Y Okazaki , V Orlando , K C Pang , W J Pavan , G Pavesi , G Pesole , N Petrovsky , S Piazza , J Reed , J F Reid , B Z Ring , M Ringwald , B Rost , Y Ruan , S L Salzberg , A Sandelin , C Schneider , C Schönbach , K Sekiguchi , C A M Semple , S Seno , L Sessa , Y Sheng , Y Shibata , H Shimada , K Shimada , D Silva , B Sinclair , S Sperling , E Stupka , K Sugiura , R Sultana , Y Takenaka , K Taki , K Tammoja , S L Tan , S Tang , M S Taylor , J Tegner , S A Teichmann , H R Ueda , E van Nimwegen , R Verardo , C L Wei , K Yagi , H Yamanishi , E Zabarovsky , S Zhu , A Zimmer , W Hide , C Bult , S M Grimmond , R D Teasdale , E T Liu , V Brusic , J Quackenbush , C Wahlestedt , J S Mattick , D A Hume , C Kai , D Sasaki , Y Tomaru , S Fukuda , M Kanamori-Katayama , M Suzuki , J Aoki , T Arakawa , J Iida , K Imamura , M Itoh , T Kato , H Kawaji , N Kawagashira , T Kawashima , M Kojima , S Kondo , H Konno , K Nakano , N Ninomiya , T Nishio , M Okada , C Plessy , K Shibata , T Shiraki , S Suzuki , M Tagami , K Waki , A Watahiki , Y Okamura-Oho , H Suzuki , J Kawai , Y Hayashizaki , FANTOM Consortium , RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) |
2005-09-02 | - |
| 15368895 |
DNA Res. Noriko Okazaki , Reiko F-Kikuno , Reiko Ohara , Susumu Inamoto , Haruhiko Koseki , Shuichi Hiraoka , Yumiko Saga , Susumu Seino , Motoi Nishimura , Tsuneyasu Kaisho , Katsuaki Hoshino , Hiroshi Kitamura , Takahiro Nagase , Osamu Ohara , Hisashi Koga |
2004-06-30 | - |
| 14610273 |
Proc. Natl. Acad. Sci. U.S.A. Brian P Zambrowicz , Alejandro Abuin , Ramiro Ramirez-Solis , Lizabeth J Richter , James Piggott , Hector BeltrandelRio , Eric C Buxton , Joel Edwards , Rick A Finch , Carl J Friddle , Anupma Gupta , Gwenn Hansen , Yi Hu , Wenhu Huang , Crystal Jaing , Billie Wayne Key , Peter Kipp , Buckley Kohlhauff , Zhi-Qing Ma , Diane Markesich , Robert Payne , David G Potter , Ny Qian , Joseph Shaw , Jeff Schrick , Zheng-Zheng Shi , Mary Jean Sparks , Isaac Van Sligtenhorst , Peter Vogel , Wade Walke , Nianhua Xu , Qichao Zhu , Christophe Person , Arthur T Sands |
2003-11-25 |
Gm14018,
Notumos,
Ldlrap1,
Mdn1,
Gm11335,
Rps12-ps4,
Gm17762,
Umad1,
BC028777,
Gm13999,
Gm9744,
Gm11696,
Dnajc3,
Rsph3b,
D030047H15Rik,
Gm10685,
Gm10876,
Gm10433,
Gm10706,
Gm15441,
Gm10787,
Apela,
Gm10640,
Dnmt3aos,
Gm10822,
Gm10687,
Gm10658,
Gm11744,
Gm10848,
Gm10535,
F420014N23Rik,
Gm16287,
Gm10463,
Fmr1os,
Gm12298,
Tmem51os1,
Gm14488,
Gm15401,
Gm10209,
Gm1976,
Gm1974,
Gm1998,
Gm13552,
Gm10031,
Gm20796,
Gm11496,
Gm2022,
Gm2050,
Gm2058,
Gm13580,
Gm2085,
Gm2087,
Gm2137,
Rps16-ps2,
Gm2183,
Gm2225,
B230206L02Rik,
Gm15706,
Gm2294,
Gm2295,
Gm2297,
Tbx3os1,
Gm2312,
Gm2315,
Gm2329,
Gm10320,
Lncenc1,
Gm2379,
Gm2381,
Gm12168,
Gm2419,
Hrct1,
Gm2428,
D5Ertd605e,
Gm2434,
Gm16020,
Gm2443,
Gm2450,
Gm2456,
Snhg12,
Gm2479,
Gm13022,
Gm2494,
Gm12184,
Gm2529,
Gm2530,
Gm2582,
Gm12193,
Gm2603,
Gm2650,
Rsf1os2,
Gm2667,
Gm13182,
Gm2672,
Gm2679,
Gm1862,
Gm2685,
Gm2695,
Gm2698
|
| 12904583 |
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Proc. Natl. Acad. Sci. U.S.A. Jens Hansen , Thomas Floss , Petra Van Sloun , Ernst-Martin Füchtbauer , Franz Vauti , Hans-Hennig Arnold , Frank Schnütgen , Wolfgang Wurst , Harald von Melchner , Patricia Ruiz |
2003-08-19 |
Mdn1,
Dnajc3,
Gm10563,
Gm9900,
Gm9888,
Gm10789,
Gm10615,
Gm2160,
Gm2272,
Lncenc1,
Gm2381,
Snhg12,
Gm10232,
Gm2695,
Gm2701,
3830408C21Rik,
Gm9825,
Gm3246,
Snhg15,
Gm13242,
Gm3325,
Gm13247,
Gm13157,
Gm15427,
Gm9800,
Gm10131,
Rex2,
1110002L01Rik,
Gm4247,
Gm14410,
Gm4419,
Gm9769,
Gm4532,
Srcap,
AI662270,
9330020H09Rik,
Camta1,
Rcc1,
Gm13225,
Phactr4,
Tmem64,
Gpn2,
AK010878,
Osbpl9,
5830417I10Rik,
Mir1902,
Mir1949,
Smpdl3b,
Bsdc1,
Gm13217,
1700007L15Rik,
Gm17251,
Gm17259,
Gm13150,
Gm19426,
Gm19446,
Gm13248,
5430416N02Rik,
Gm12588,
Snhg4,
Gm13147,
Gm19702,
Gm19705,
Platr22,
Gm19771,
Zfp534,
Gm16740,
AU020206,
Gm20179,
2900076A07Rik,
Gm15834,
Gm10374,
Zfp518b,
Gm14401,
AI480526,
Tbc1d14,
Akap9,
Zfp513,
Gm29787,
Tra2a,
Brk1,
Mirc35hg,
Phrf1,
Plekha1,
Numa1,
Sf3b3,
Champ1,
Gadd45gip1,
Arhgef18,
Dohh,
Fam192a,
Taf5l,
Ankrd10,
Cog4,
4930512M02Rik,
Gm30000,
Gm30214,
Gm30370,
Gm31005
|
| 12520002 |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Nucleic Acids Res. Doug Stryke , Michiko Kawamoto , Conrad C Huang , Susan J Johns , Leslie A King , Courtney A Harper , Elaine C Meng , Roy E Lee , Alice Yee , Larry L'Italien , Pao-Tien Chuang , Stephen G Young , William C Skarnes , Patricia C Babbitt , Thomas E Ferrin |
2003-01-01 | - |
| 12477932 |
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team |
2002-12-24 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员