| Type | Description |
|---|---|
| Definition | T cell lymphoma invasion and metastasis 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-16 12:37:00 | TIAM1 is overexpressed in colorectal cancer (CRC) tumors from patients who did not respond to chemotherapeutic drugs and levels of TIAM1 expression served as an independent prognostic factor. Cancer associated fibroblasts enhanced CRC chemoresistance through TIAM1 overexpression. These results suggest that TIAM1 regulates chemosensitivity in tumors and stroma and thus may be an attractive therapeutic target. | 30890693 |
| 2020-01-18 12:15:00 | Results suggest that miR-142-5p and T-cell lymphoma invasion and metastasis 1 (Tiam1) may be potential diagnostic markers for colon cancer. | 31854959 |
| 2019-11-23 10:57:00 | The meta-analysis confirmed that Tiam1 higher expression positively correlated with OS and DFS, suggesting that Tiam1 may act as a valuable prognostic predictor. | 31702612 |
| 2019-03-16 12:49:00 | our study demonstrated that upregulation of Tiam1 contributes to cervical cancer disease progression and indicates poor survival outcome | 29452216 |
| 2019-01-26 11:09:00 | Overexpression of miR-10b in HeLa and SiHa suppressed cell proliferation, migration and invasion, and induced apoptosis and miR-10b downregulation had opposite effects. Mechanistically, T-cell lymphoma invasion and metastasis 1 (Tiam1) was identified as a direct and functional target of miR-10b. | 30504727 |
| Type | IDs |
|---|---|
| Synonymous | TIAM-1 |
| Gene |
UniProtKB-ID:
TIAM1_HUMAN,
A0A2X0TW27_HUMAN
UniprotKB:
Q13009,
A0A2X0TW27
UniParc:
UPI0002065410,
UPI000013DE6F
EMBL:
BC117196,
AP000251,
BC143980,
AP000563,
AP000250,
U16296,
LS482429,
AP000247,
AP000249,
AP000246,
BC117192,
CH471079,
AP000248
Ensembl:
ENSG00000156299
KO:
hsa:7074
|
| Nucleutide sequences |
EMBL-CDS:
AAI17197.1,
AAA98443.1,
AAI43981.1,
AAI17193.1,
SPT35806.1,
EAX09895.1
Gene_ORFName:
hCG_401145
Ensembl_TRS:
ENST00000541036,
ENST00000286827
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000286827,
ENSP00000441570
RefSeq:
NP_001340617.1,
NP_001340622.1,
XP_024307895.1,
NP_001340621.1,
XP_005261095.1,
NP_001340615.1,
XP_005261097.1,
NP_001340616.1,
XP_011528014.1,
NP_001340623.1,
XP_016883940.1,
NP_001340613.1,
XP_011528015.1,
NP_001340619.1,
NP_001340618.1,
XP_016883939.1,
XP_016883937.1,
NP_001340614.1,
NP_001340620.1,
NP_003244.2
|
| Others |
UniRef100:
UniRef100_Q13009
UniRef90:
UniRef90_Q13009
UniRef50:
UniRef50_Q13009
UniGene:
Hs.517228
CCDS:
CCDS13609.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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