| Type | Description |
|---|---|
| Definition | TIA1 cytotoxic granule associated RNA binding protein like 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-08-17 10:08:00 | Depletion of TIAR accelerates mitotic entry and leads to chromosomal instability in response to replication stress, in a manner that can be alleviated by the concomitant depletion of Cdc25B or inhibition of CDK1. Since TIAR retains CDK1 in GMGs and attenuates CDK1 activity, we propose that the assembly of GMGs may represent a so far unrecognized mechanism that contributes to the activation of the G2/M checkpoint | 30538118 |
| 2019-06-01 12:43:00 | The manipulation of miR2233p/TIAL1 interaction may be involved in the neuroprotective effects of DEX. | 30569136 |
| 2018-01-20 11:39:00 | Data indicate that both ELAVL1 and TIAR positively regulate endogenous SNCA in vivo. | 29149290 |
| 2017-12-16 12:38:00 | we identified MT1JP as a critical factor in restraining cell transformation by modulating p53 translation through interactions with TIAR | 26909858 |
| 2017-06-24 10:27:00 | Data suggest that TPD52 (tumor protein D52) and a TPD52 fragment (residues 78-280) along with TIA-1 (T-cell intracellular antigen-1) and TIAR (TIA-1-related protein) contribute to mRNA stability as cis-acting and trans-acting factors; 3prime-untranslated regions of TPD52, TPD53, and TPD54 regulate expression of their respective genes in a post-transcriptional manner by altering mRNA stability. | 28298474 |
| Type | IDs |
|---|---|
| Synonymous | TCBP, TIAR |
| Gene |
UniProtKB-ID:
TIAR_HUMAN,
Q49AS9_HUMAN
UniprotKB:
Q01085,
Q49AS9
UniParc:
UPI00004BEBE5,
UPI0000136F4F,
UPI0000404AF4
EMBL:
AK290984,
BC030025,
AK290695,
M96954
Ensembl:
ENSG00000151923
KO:
hsa:7073
|
| Nucleutide sequences |
EMBL-CDS:
BAF83673.1,
AAA36384.1,
BAF83384.1,
AAH30025.1
Ensembl_TRS:
ENST00000369093,
ENST00000436547
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000394902,
ENSP00000358089
RefSeq:
XP_024303919.1,
NP_003243.1,
NP_001310893.1,
NP_001029097.1,
NP_001310897.1,
NP_001310896.1,
NP_001310899.1,
NP_001310894.1,
NP_001310898.1
|
| Others |
UniRef100:
UniRef100_Q49AS9,
UniRef100_Q01085
UniRef90:
UniRef90_Q01085,
UniRef90_Q49AS9
UniRef50:
UniRef50_Q01085,
UniRef50_A0A5F4D0W2
UniGene:
Hs.501203
CCDS:
CCDS31295.1,
CCDS7613.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员