| Type | Description |
|---|---|
| Definition | nitric oxide synthase 1 (neuronal) adaptor protein |
| Date | Results | Publications |
|---|---|---|
| 2020-10-10 12:57:00 | CAPON Is a Critical Protein in Synaptic Molecular Networks in the Prefrontal Cortex of Mood Disorder Patients and Contributes to Depression-Like Behavior in a Mouse Model. | 30307500 |
| 2019-11-30 11:55:00 | nNOS-CAPON interaction may function via regulating structural neuroplasticity, rather than neuroprotection | 30727847 |
| 2019-09-14 10:07:00 | In models of Alzheimer's disease, increased nNOS-CAPON interaction was detected after treatment with amyloid-beta in vitro, and a similar change was found in the hippocampus of APP/PS1 mice (a transgenic mouse model of Alzheimer's disease), compared with age-matched background mice in vivo. | 29577585 |
| 2019-06-29 11:18:00 | CAPON accumulated in the hippocampal pyramidal cell layer in the App(NL-G-F) -knock-in (KI) brain. In a model of Alzheimer's disease, CAPON overexpression produced significant hippocampal atrophy and caspase3-dependent neuronal cell death in the CAPON-expressing hippocampus, suggesting that CAPON accumulation increases neurodegeneration. | 31160584 |
| 2017-05-07 00:05:00 | results hint towards an involvement of NOS-I/NOS1AP interaction in the regulation of dendritic spine plasticity | 26861996 |
| Type | IDs |
|---|---|
| Synonymous | 6330408P19Rik, Capon |
| Gene |
UniProtKB-ID:
CAPON_MOUSE
UniprotKB:
Q9D3A8
UniParc:
UPI000217CB12,
UPI0000D62DBE
EMBL:
AK018149,
AK122290,
AC125017,
AC119431,
AC123650,
AC125021
Ensembl:
ENSMUSG00000038473
KO:
mmu:70729
|
| Nucleutide sequences |
EMBL-CDS:
BAB31095.1,
BAC65572.3
Ensembl_TRS:
ENSMUST00000160456
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000125251
RefSeq:
NP_001103455.1
|
| Others |
UniRef100:
UniRef100_Q9D3A8
UniRef90:
UniRef90_Q9D3A8
UniRef50:
UniRef50_Q9D3A8
UniGene:
Mm.487078
CCDS:
CCDS48438.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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