| Type | Description |
|---|---|
| Definition | angiopoietin-like 6 |
| Date | Results | Publications |
|---|---|---|
| 2018-11-10 11:14:00 | Since upregulation of ANGPTL6 is induced on metabolic stress, we investigated the hepatic expression of ANGPTL6 by leptin, a representative adipokine of obesity. Mice on a high-fat diet showed increased serum leptin levels and hepatic Angptl6 expression. | 29852166 |
| 2018-06-23 10:19:00 | Upregulation of ANGPTL6 in mouse keratinocytes enhances susceptibility to psoriasis. | 27698489 |
| 2017-06-24 11:27:00 | mitochondrial OXPHOS function governs the expression of ANGPTL6, which is an essential factor for FGF21 production in adipose tissue and cultured adipocytes. | 28184000 |
| 2012-07-28 11:06:00 | In addition to pronounced angiogenesis and epidermal hyperplasia, marked enlargement of dermal lymphatic vessels was observed in UV-B-exposed Angptl6/AGF transgenic mice. | 22132739 |
| 2010-01-21 00:00:00 | we show that (>80%) of the AGF-deficient mice die at about embryonic day 13, while the surviving AGF-deficient mice develop marked obesity, lipid accumulation in skeletal muscle and liver, and insulin resistance accompanied by reduced energy expenditure | 15778720 |
| Type | IDs |
|---|---|
| Synonymous | 6330404E11Rik, AGF, ARP3, Arp5 |
| Gene |
UniProtKB-ID:
ANGL6_MOUSE
UniprotKB:
Q8R0Z6
UniParc:
UPI0000027D40
EMBL:
BC025904,
AB054065
Ensembl:
ENSMUSG00000038742
KO:
mmu:70726
|
| Nucleutide sequences |
EMBL-CDS:
AAH25904.1,
BAB91249.1
Ensembl_TRS:
ENSMUST00000043726
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000035784
RefSeq:
XP_011240902.1,
NP_660136.1,
XP_011240901.1
|
| Others |
UniRef100:
UniRef100_Q8R0Z6
UniRef90:
UniRef90_Q8R0Z6
UniRef50:
UniRef50_Q8R0Z6
UniGene:
Mm.34019
CCDS:
CCDS22886.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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