| Type | Description |
|---|---|
| Definition | dual specificity phosphatase 16 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-26 13:03:00 | Targeting DUSP16/TAK1 signaling alleviates hepatic dyslipidemia and inflammation in high fat diet (HFD)-challenged mice through suppressing JNK MAPK. | 31982140 |
| 2020-05-23 11:32:00 | Studies in knockout mice show that DUSP16 is an endogenous regulator of OPN-type osteoblast differentiation, via JNK dephosphorylation by DUSP16. | 30884976 |
| 2017-07-22 10:05:00 | Ablation of Dusp16 enhanced axonal degeneration in response to trophic withdrawal, suggesting that it has a protective function. Moreover, axonal skin innervation was severely reduced while neuronal elimination was increased in the Dusp16 knockout. Mechanistically, Dusp16 negatively regulates the transcription factor p53 and antagonizes the expression of the pro-degenerative factor, Puma. | 27889097 |
| 2015-06-20 12:46:00 | MAPK phosphatase 7 regulates T cell differentiation via inhibiting ERK-mediated IL-2 expression. | 25716993 |
| 2015-06-06 11:53:00 | ADCY5 repression by miR-17 facilitated the translocation of EGFR and MKP7 from membrane into cytoplasmic and mitochondrial fractions. | 25077541 |
| Type | IDs |
|---|---|
| Synonymous | 3830417M17Rik, AW558566, D6Ertd213e, MKP-7, MKP7, Mkpm |
| Gene |
UniProtKB-ID:
F6UIK0_MOUSE,
Q6PCP3_MOUSE
UniprotKB:
F6UIK0,
Q6PCP3
UniParc:
UPI0000023416,
UPI0000DE2393
EMBL:
AC122193,
BC059232,
AC126692,
BC057321
Ensembl:
ENSMUSG00000030203
KO:
mmu:70686
|
| Nucleutide sequences |
EMBL-CDS:
AAH59232.1,
AAH57321.1
Ensembl_TRS:
ENSMUST00000129433,
ENSMUST00000100857
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000115925,
ENSMUSP00000098419
RefSeq:
NP_569714.2,
NP_001041519.1,
XP_036008192.1,
XP_036008191.1
|
| Others |
UniRef100:
UniRef100_F6UIK0,
UniRef100_Q6PCP3
UniRef90:
UniRef90_F6UIK0,
UniRef90_Q920R2
UniRef50:
UniRef50_Q920R2,
UniRef50_F6UIK0
UniGene:
Mm.491182
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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