| Type | Description |
|---|---|
| Definition | SIK family kinase 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-22 15:31:00 | The AMPK-Related Kinases SIK1 and SIK3 Mediate Key Tumor-Suppressive Effects of LKB1 in NSCLC. | 31350328 |
| 2020-06-06 12:02:00 | Deletion of Sik3 delays the maturation of chondrocytes. Acetyl-CoA was decreased and Pdk4 expression was increased in Sik3-deficient chondrocytes. | 31280862 |
| 2019-04-13 10:45:00 | Mutant Gnas is critical for pancreatic tumour tumorigenesis, driven by protein-kinase-A-mediated suppression of salt-inducible kinases (Sik1-3), and associated with induction of lipid remodelling and fatty acid oxidation. | 29941929 |
| 2018-11-17 10:56:00 | evolutionally conserved S551 of SIK3 mediates, together with and 14-3-3, the intracellular signaling crucial for the regulation of daily sleep amounts and sleep need at the organismal level | 30254177 |
| 2018-08-04 11:19:00 | Collectively, SIK3 plays key roles in circadian rhythms by facilitating phosphorylation-dependent PER2 destabilization, either directly or indirectly. | 29227248 |
| Type | IDs |
|---|---|
| Synonymous | 5730525O22Rik, 9030204A07Rik, AI447252, AI846254, AI849445, Qsk, SIK-3, mKIAA0999 |
| Gene |
UniProtKB-ID:
SIK3_MOUSE,
E9PU87_MOUSE
UniprotKB:
Q6P4S6,
E9PU87
UniParc:
UPI000042903B,
UPI00000E8542,
UPI0000E2626D
EMBL:
BC082313,
AC122273,
AK017789,
AK129257,
BC063268,
BC080688,
AC116503,
BC033915
Ensembl:
ENSMUSG00000034135
KO:
mmu:70661
|
| Nucleutide sequences |
EMBL-CDS:
AAH80688.1,
AAH63268.2,
BAB30934.1,
BAC98067.1,
AAH82313.1,
AAH33915.1
Ensembl_TRS:
ENSMUST00000126865
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000121032
RefSeq:
XP_006510653.1,
NP_081774.3
|
| Others |
UniRef100:
UniRef100_Q6P4S6,
UniRef100_E9PU87
UniRef90:
UniRef90_Q6P4S6
UniRef50:
UniRef50_Q9Y2K2
UniGene:
Mm.219459
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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