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7066 THPO

7066

THPO

thrombopoietin

protein-coding

Homo sapiens

基因描述

Type Description
Definition thrombopoietin

研究结论

Date Results Publications
2021-04-17 13:16:00 Cooperative Role of Thrombopoietin and in the Progression of Liver Cirrhosis to Hepatocellular Carcinoma. 33673041
2021-03-06 13:32:00 A novel thrombopoietin (THPO) mutation altering mRNA splicing in a case of familial thrombocytosis. 32430933
2021-02-27 13:49:00 c-Mpl and TPO expression in the human central nervous system neurons inhibits neuronal apoptosis. 32341206
2020-05-23 12:14:00 The antibody affinity and autoantigenicity of thrombopoietin (TPO) might be reduced, if the conformational variability of hTPO163 is restricted by mutation and/or by the addition of C-terminal domain with glycosylation to keep its conformation suitable for the c-Mpl recognition. 30675759
2020-02-22 13:04:00 Data suggest that thrombopoietin (TPO) elevation and associated increased platelet production may be one driver of early extreme post-total pancreatectomy with islet autotransplantation thrombocytosis, and this process may be modulated by hydroxyurea. 31091211

名称对应

Type IDs
Synonymous MGDF, MKCSF, ML, MPLLG, THCYT1, TPO
Gene
UniProtKB-ID: TPO_HUMAN, Q5FBX8_HUMAN, F8W6L1_HUMAN, A0A3B3ITS0_HUMAN
UniprotKB: P40225, Q5FBX8, F8W6L1, A0A3B3ITS0
UniParc: UPI0000EE22C7, UPI00004CA0DD, UPI000004A8D1, UPI000002B5BB, UPI000002B5BC, UPI0000148CB2
EMBL: BC136338, L36051, D32046, U17071, BC130322, L33410, U11025, U59493, AB102890, U59494, U59495, CH471052, AC078797, S76771, BC143982, D32047, L36052
Ensembl: ENSG00000090534
KO: hsa:7066
Nucleutide sequences
EMBL-CDS: AAB03394.1, AAI43983.1, AAA59857.1, BAA06807.1, AAA50553.1, AAB03393.1, AAA74083.1, AAB33390.1, AAC37568.1, AAI30323.1, AAC37566.1, AAB03392.1, AAI36339.1, BAA21930.1, BAD89419.1, EAW78245.1
Gene_ORFName: hCG_40497
Ensembl_TRS: ENST00000647395, ENST00000445696, ENST00000650229, ENST00000421442, ENST00000649095, ENST00000645603
Protein sequencees
Ensembl_PRO: ENSP00000494504, ENSP00000410763, ENSP00000497233, ENSP00000411704, ENSP00000497904, ENSP00000494281
RefSeq: NP_001276932.1, NP_001171068.1, NP_001276957.1, NP_001171069.1, NP_000451.1, NP_001276926.1, NP_001276955.1, NP_001276956.1, XP_016862596.1, NP_001276951.1, NP_001276927.1
Others
UniRef100: UniRef100_P40225, UniRef100_F8W6L1, UniRef100_Q5FBX8
UniRef90: UniRef90_P40225, UniRef90_Q5FBX8
UniRef50: UniRef50_P40225
UniGene: Hs.1166, Hs.734657
CCDS: CCDS3265.1, CCDS54693.1

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