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7064 THOP1

7064

THOP1

thimet oligopeptidase 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition thimet oligopeptidase 1

研究结论

Date Results Publications
2017-11-11 11:52:00 Data suggest that three new candidate genes involved in the development of rheumatoid arthritis (RA): ERBB2, TP53 and THOP1. 28148290
2015-11-07 11:49:00 THOP1 may have clinical potentials to be employed as a promising biomarker to identify individuals with better prognosis and a novel antitumor agent for therapy of patients with NSCLC 25180910
2015-01-24 13:10:00 Low THOP1 expression levels are associated with recurrence of hepatocellular carcinoma. 24604581
2014-08-30 12:34:00 TCEP. Data indicate that THIMET-oligopeptidase (TOP) oxidation by H2O2 and high valence states of hemeproteins does not lead to enzyme oligomerization. 24223886
2014-03-01 10:44:00 shear-dependent TOP induction down-regulates MHC1 levels, pointing to a role for TOP in the flow-mediated regulation of endothelial immunogenicity 23708739

名称对应

Type IDs
Synonymous EP24.15, MEPD_HUMAN, MP78, TOP
Gene
UniProtKB-ID: THOP1_HUMAN
UniprotKB: P52888
UniParc: UPI0000000C3E, UPI0000140356
EMBL: AC006538, U29366, AK093392, Z50115, BC002391, BC000135
Ensembl: ENSG00000172009
KO: hsa:7064
Nucleutide sequences
EMBL-CDS: CAA90477.1, AAH02391.1, BAG52704.1, AAH00135.1, AAA82607.1, AAD13118.1
Ensembl_TRS: ENST00000395212, ENST00000307741
Protein sequencees
Ensembl_PRO: ENSP00000378638, ENSP00000304467
RefSeq: XP_011526530.1, NP_003240.1
Others
UniRef100: UniRef100_P52888
UniRef90: UniRef90_P52888
UniRef50: UniRef50_P52888
UniGene: Hs.78769
CCDS: CCDS12095.1

全选

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研究热度

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