| Type | Description |
|---|---|
| Definition | trichohyalin |
| Date | Results | Publications |
|---|---|---|
| 2017-09-16 11:48:00 | The difference between the twoinduced pluripotent stem cell(IPSC) clones in TCHH methylation did not have an obvious effect on its expression in 3D human epidermal equivalent, suggesting that differentiation and tissue formation may mitigate variations in the iPSC methylome. | 27460132 |
| 2017-05-27 12:16:00 | The two enzymes and TGM3, responsible for posttranslational protein modifications, and their target structural protein TCHH are all involved in hair shaft formation. | 27866708 |
| 2017-05-20 12:20:00 | To evaluate the relative contribution of these variants, we performed a second genome-wide scan in 709 samples from the Uyghur, an admixed population with both eastern and western Eurasian ancestries. In Uyghurs, both EDAR (rs3827760: P = 1.92 x 10(-12)) and TCHH (rs11803731: P = 1.46 x 10(-3)) are associated with hair straightness, but EDAR (OR 0.415) has a greater effect than TCHH (OR 0.575). | 27487801 |
| 2010-10-30 10:43:00 | Data suggest that an immune response to trichohyalin and K16 may have a role in the pathogenesis of the enigmatic disorder. | 20722389 |
| 2010-09-15 22:05:00 | Observational study of gene-disease association. (HuGE Navigator) | 20585627 |
| Type | IDs |
|---|---|
| Synonymous | THH, THL, TRHY, UHS3 |
| Gene |
UniProtKB-ID:
TRHY_HUMAN
UniprotKB:
Q07283
UniParc:
UPI0000458A5E
EMBL:
AL589986,
L09190
Ensembl:
ENSG00000159450
KO:
hsa:7062
|
| Nucleutide sequences |
EMBL-CDS:
AAA65582.1
Ensembl_TRS:
ENST00000368804,
ENST00000614923
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000357794,
ENSP00000480484
RefSeq:
NP_009044.2
|
| Others |
UniRef100:
UniRef100_Q07283
UniRef90:
UniRef90_Q07283
UniRef50:
UniRef50_Q07283
UniGene:
Hs.432416
CCDS:
CCDS41396.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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