| Type | Description |
|---|---|
| Definition | mutY DNA glycosylase |
| Date | Results | Publications |
|---|---|---|
| 2020-12-12 13:24:00 | The DNA repair enzyme MUTYH potentiates cytotoxicity of the alkylating agent MNNG by interacting with abasic sites. | 32001618 |
| 2019-10-12 12:38:00 | These findings suggest that MUTYH does not rely upon the wedge residue for damage site recognition, but this residue stabilizes the lesion recognition complex. | 30698731 |
| 2017-12-30 10:48:00 | results suggested that MYH, which interacts with TRADD, inhibits TNF-alpha necroptotic signaling. Therefore, MYH inactivation is essential for necroptosis via the downregulation of caspase-8. | 28059467 |
| 2016-11-05 11:04:00 | Ogg1 and Mutyh regulate hippocampal gene expression related to cognition and behavior, suggesting a role for the glycosylases in regulating adaptive behavior. | 26711335 |
| 2016-05-28 10:18:00 | MUTYH loss is associated with an increase in inflammation associated colorectal cancer risk, which involves immunosuppression and altered inflammatory response. | 26109431 |
| Type | IDs |
|---|---|
| Synonymous | 5730495A01Rik, Mutyha, Mutyhalpha, Mutyhb, Mutyhbeta, Mutyhc, Myh |
| Gene |
UniProtKB-ID:
MUTYH_MOUSE,
Q762C9_MOUSE,
Q762D1_MOUSE
UniprotKB:
Q99P21,
Q762C9,
Q762D1
UniParc:
UPI00001D4911,
UPI0000022F78,
UPI00001D4912
EMBL:
AY007717,
BC057942,
AL683847,
AB117938,
AB117937,
AB117939
Ensembl:
ENSMUSG00000028687
KO:
mmu:70603
|
| Nucleutide sequences |
EMBL-CDS:
BAC98380.1,
AAG16632.1,
AAH57942.1,
BAC98381.1,
BAC98379.1
Ensembl_TRS:
ENSMUST00000102699
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000099760
RefSeq:
XP_036020311.1,
NP_001303676.1,
XP_006503455.1,
NP_001153053.1,
NP_573513.2,
XP_030109634.1,
XP_036020312.1,
XP_030109635.1
|
| Others |
UniRef100:
UniRef100_Q762D1,
UniRef100_Q99P21
UniRef90:
UniRef90_Q762D1,
UniRef90_Q99P21
UniRef50:
UniRef50_Q99P21
UniGene:
Mm.180333
CCDS:
CCDS18518.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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