Functional genomic landscape of cancer-intrinsic evasion of killing by T cells.

Nature     Keith A Lawson , Cristovão M Sousa , Xiaoyu Zhang , Eiru Kim , Rummy Akthar , Joseph J Caumanns , Yuxi Yao , Nicholas Mikolajewicz , Catherine Ross , Kevin R Brown , Abdelrahman Abou Zid , Zi Peng Fan , Shirley Hui , Jordan A Krall , Donald M Simons , Chloe J Slater , Victor De Jesus , Lujia Tang , Richa Singh , Joshua E Goldford , Sarah Martin , Qian Huang , Elizabeth A Francis , Andrea Habsid , Ryan Climie , David Tieu , Jiarun Wei , Ren Li , Amy Hin Yan Tong , Michael Aregger , Katherine S Chan , Hong Han , Xiaowei Wang , Patricia Mero , John H Brumell , Antonio Finelli , Laurie Ailles , Gary Bader , Gromoslaw A Smolen , Gillian A Kingsbury , Traver Hart , Charles Kung , Jason Moffat

A Wars2 Mutant Mouse Model Displays OXPHOS Deficiencies and Activation of Tissue-Specific Stress Response Pathways.

Cell Rep     Thomas Agnew , Michelle Goldsworthy , Carlos Aguilar , Anna Morgan , Michelle Simon , Helen Hilton , Chris Esapa , Yixing Wu , Heather Cater , Liz Bentley , Cheryl Scudamore , Joanna Poulton , Karl J Morten , Kyle Thompson , Langping He , Steve D M Brown , Robert W Taylor , Michael R Bowl , Roger D Cox

High-throughput discovery of novel developmental phenotypes.

Nature     Mary E Dickinson , Ann M Flenniken , Xiao Ji , Lydia Teboul , Michael D Wong , Jacqueline K White , Terrence F Meehan , Wolfgang J Weninger , Henrik Westerberg , Hibret Adissu , Candice N Baker , Lynette Bower , James M Brown , L Brianna Caddle , Francesco Chiani , Dave Clary , James Cleak , Mark J Daly , James M Denegre , Brendan Doe , Mary E Dolan , Sarah M Edie , Helmut Fuchs , Valerie Gailus-Durner , Antonella Galli , Alessia Gambadoro , Juan Gallegos , Shiying Guo , Neil R Horner , Chih-Wei Hsu , Sara J Johnson , Sowmya Kalaga , Lance C Keith , Louise Lanoue , Thomas N Lawson , Monkol Lek , Manuel Mark , Susan Marschall , Jeremy Mason , Melissa L McElwee , Susan Newbigging , Lauryl M J Nutter , Kevin A Peterson , Ramiro Ramirez-Solis , Douglas J Rowland , Edward Ryder , Kaitlin E Samocha , John R Seavitt , Mohammed Selloum , Zsombor Szoke-Kovacs , Masaru Tamura , Amanda G Trainor , Ilinca Tudose , Shigeharu Wakana , Jonathan Warren , Olivia Wendling , David B West , Leeyean Wong , Atsushi Yoshiki , International Mouse Phenotyping Consortium , Jackson Laboratory , Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris (ICS) , Charles River Laboratories , MRC Harwell , Toronto Centre for Phenogenomics , Wellcome Trust Sanger Institute , RIKEN BioResource Center , Daniel G MacArthur , Glauco P Tocchini-Valentini , Xiang Gao , Paul Flicek , Allan Bradley , William C Skarnes , Monica J Justice , Helen E Parkinson , Mark Moore , Sara Wells , Robert E Braun , Karen L Svenson , Martin Hrabe de Angelis , Yann Herault , Tim Mohun , Ann-Marie Mallon , R Mark Henkelman , Steve D M Brown , David J Adams , K C Kent Lloyd , Colin McKerlie , Arthur L Beaudet , Maja Bućan , Stephen A Murray

Novel gene function revealed by mouse mutagenesis screens for models of age-related disease.

Nat Commun     Paul K Potter , Michael R Bowl , Prashanthini Jeyarajan , Laura Wisby , Andrew Blease , Michelle E Goldsworthy , Michelle M Simon , Simon Greenaway , Vincent Michel , Alun Barnard , Carlos Aguilar , Thomas Agnew , Gareth Banks , Andrew Blake , Lauren Chessum , Joanne Dorning , Sara Falcone , Laurence Goosey , Shelley Harris , Andy Haynes , Ines Heise , Rosie Hillier , Tertius Hough , Angela Hoslin , Marie Hutchison , Ruairidh King , Saumya Kumar , Heena V Lad , Gemma Law , Robert E MacLaren , Susan Morse , Thomas Nicol , Andrew Parker , Karen Pickford , Siddharth Sethi , Becky Starbuck , Femke Stelma , Michael Cheeseman , Sally H Cross , Russell G Foster , Ian J Jackson , Stuart N Peirson , Rajesh V Thakker , Tonia Vincent , Cheryl Scudamore , Sara Wells , Aziz El-Amraoui , Christine Petit , Abraham Acevedo-Arozena , Patrick M Nolan , Roger Cox , Anne-Marie Mallon , Steve D M Brown

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.

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Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.

Brief. Bioinformatics     Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas

Species-specific differences in the regulation of the aminoacylation activity of mammalian tryptophanyl-tRNA synthetases.

FEBS Lett.     Keisuke Wakasugi

A mitochondrial protein compendium elucidates complex I disease biology.

Cell     David J Pagliarini , Sarah E Calvo , Betty Chang , Sunil A Sheth , Scott B Vafai , Shao-En Ong , Geoffrey A Walford , Canny Sugiana , Avihu Boneh , William K Chen , David E Hill , Marc Vidal , James G Evans , David R Thorburn , Steven A Carr , Vamsi K Mootha

T2-TrpRS inhibits preretinal neovascularization and enhances physiological vascular regrowth in OIR as assessed by a new method of quantification.

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The transcriptional landscape of the mammalian genome.

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