| Type | Description |
|---|---|
| Definition | TGFB induced factor homeobox 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:25:00 | XTP8 stimulates migration and invasion of gastric carcinoma through interacting with TGIF1. | 32196592 |
| 2020-10-03 12:54:00 | Breast cancer bone metastases are attenuated in a Tgif1-deficient bone microenvironment. | 32272947 |
| 2020-05-09 12:33:00 | KDM5B-mediated miR-448 up-regulation restrains papillary thyroid cancer cell progression and slows down tumor growth via TGIF1 repression | 32147429 |
| 2020-04-18 10:12:00 | Study report that TGIF1 is appreciably inactivated during pancreatic ductal adenocarcinoma (PDAC) progression and suggest that TGIF1 might serve as a potential prognostic indicator for PDAC progression. Also, TGIF1 loss accelerates PDAC development with reduced survival and increased metastatic behaviors in cooperation with KrasG12D. | 31109321 |
| 2019-12-28 12:27:00 | Findings pinpoint TGIF1 as a potential tumor suppressor in pancreatic ductal adenocarcinoma and further suggest that sustained activation of TGF-b signaling might act to accelerate PDAC progression rather than to suppress its initiation. | 31268604 |
| Type | IDs |
|---|---|
| Synonymous | HPE4, TGIF |
| Gene |
UniProtKB-ID:
TGIF1_HUMAN
UniprotKB:
Q15583
UniParc:
UPI000016106A,
UPI0000140386,
UPI0000136CC2,
UPI0000160FE7
EMBL:
BC000814,
CR450333,
X89750,
AP001025,
AK291112,
BE296707,
CH471113,
BC031268,
AF179900
Ensembl:
ENSG00000177426
KO:
hsa:7050
|
| Nucleutide sequences |
EMBL-CDS:
AAH00814.1,
BAF83801.1,
CAG29329.1,
AAH31268.1,
AAF81643.1,
CAA61897.1,
EAX01672.1
Ensembl_TRS:
ENST00000330513,
ENST00000401449,
ENST00000548489,
ENST00000407501,
ENST00000618001,
ENST00000400167,
ENST00000345133,
ENST00000405385,
ENST00000472042,
ENST00000551541,
ENST00000343820
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000343969,
ENSP00000385206,
ENSP00000327959,
ENSP00000449501,
ENSP00000383031,
ENSP00000339631,
ENSP00000447747,
ENSP00000384133,
ENSP00000450025,
ENSP00000384970,
ENSP00000483499
RefSeq:
NP_001361325.1,
NP_775301.1,
NP_003235.1,
NP_001265613.1,
NP_775300.1,
XP_016881447.1,
NP_001361326.1,
NP_733796.3,
NP_001265611.1,
NP_775302.1,
NP_775299.1,
NP_001265615.1,
NP_775303.1,
NP_777480.1
|
| Others |
UniRef100:
UniRef100_Q15583
UniRef90:
UniRef90_Q15583
UniRef50:
UniRef50_Q15583
UniGene:
Hs.373550
CCDS:
CCDS11832.1,
CCDS11835.1,
CCDS11834.1,
CCDS11833.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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