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70465 Wdr77

70465

Wdr77

WD repeat domain 77

protein-coding

Mus musculus

基因描述

Type Description
Definition WD repeat domain 77

研究结论

Date Results Publications
2020-08-12 15:30:00 MEP50 associated with the purinergic receptor P2X5 and is involved in osteoclast maturation. 31432503
2019-03-02 11:07:00 Wdr77 ablation inhibited E2F3 activation and enhanced TGFbeta signaling, leading to attenuated cellular proliferation induced by loss of Pten. 29706654
2017-06-10 13:07:00 WDR77 expression is associated with E2F1, E2F3, GATA2 and GATA6 occupancy on the WDR77 gene, whereas, in contrast, E2F6, GATA1 and GATA3 occupancy is associated with the loss of WDR77 expression during erythroid maturation and lung development 27274086
2015-01-31 11:08:00 These findings characterize PKG as a novel regulator of AR-mediated transcription by enhancing AR cofactor p44/WDR77's function. 23755100
2013-06-22 10:13:00 p44/wdr77 controls cellular proliferation during lung development, and this growth process is reactivated during lung tumorigenesis 22665061

名称对应

Type IDs
Synonymous 2610003I18Rik, 2610312E17Rik, C79984, p44/MEP50
Gene
UniProtKB-ID: MEP50_MOUSE
UniprotKB: Q99J09
UniParc: UPI0000021187
EMBL: AK012014, AK050391, AK048488, AK032897, BC005755, AK169128, AK163839
Ensembl: ENSMUSG00000000561
KO: mmu:70465
Nucleutide sequences
EMBL-CDS: BAC33350.1, BAE37512.1, AAH05755.1, BAC28076.1, BAE40907.1, BAC34232.1, BAB27975.1
Ensembl_TRS: ENSMUST00000010278
Protein sequencees
Ensembl_PRO: ENSMUSP00000010278
RefSeq: NP_081708.1
Others
UniRef100: UniRef100_Q99J09
UniRef90: UniRef90_Q99J09
UniRef50: UniRef50_Q9BQA1-2
UniGene: Mm.5110
CCDS: CCDS17715.1

全选

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研究热度

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