| Type | Description |
|---|---|
| Definition | CREB regulated transcription coactivator 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-25 11:16:00 | The results demonstrate that the localization of CRTC3 involves in regulating cold-induced upregulation of UCP1 in BAT and provide useful information for understanding the molecular regulation of BAT thermogenesis induced by a cold environment. | 30506739 |
| 2018-09-08 11:51:00 | CRTC3 reduced sympathetic nerve activity in BAT by up-regulating the expression of miR-206, a microRNA that promotes differentiation along the myogenic lineage and that we show here decreases the expression of VEGFA and neurotrophins critical for BAT innervation and vascularization. | 29784793 |
| 2018-09-01 10:30:00 | Deletion of Lkb1 results in a cytoplasm to nuclear translocation of CRTC3 in brown adipocytes, where it recruits C/EBPbeta to enhance Ucp1 transcription. | 27461402 |
| 2018-06-23 10:23:00 | These results demonstrate how cross-coupling between the CREB/CRTC and pathways contributes to bone marrow homeostasis. | 29078378 |
| 2017-10-14 10:41:00 | the existence of an unusual functional interplay between and CREB at the onset of adipogenesis through shared CRTC cofactors, is reported. | 27362806 |
| Type | IDs |
|---|---|
| Synonymous | 2610312F20Rik, 6332415K15Rik, AI429792, BC011210, TORC3 |
| Gene |
UniProtKB-ID:
CRTC3_MOUSE
UniprotKB:
Q91X84
UniParc:
UPI000002350F,
UPI0000357B33
EMBL:
BC011210,
AK144840
Ensembl:
ENSMUSG00000030527
KO:
mmu:70461
|
| Nucleutide sequences |
EMBL-CDS:
AAH11210.1
Ensembl_TRS:
ENSMUST00000122255
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000113540
RefSeq:
XP_030098841.1,
XP_006541258.1,
NP_776288.2
|
| Others |
UniRef100:
UniRef100_Q91X84
UniRef90:
UniRef90_Q91X84
UniRef50:
UniRef50_Q91X84
UniGene:
Mm.392175
CCDS:
CCDS21398.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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